Temperature influences the interaction of ruminant PrP (TSE) with soil.

Prion
Ben C MaddisonKevin C Gough

Abstract

Ovine scrapie and cervid chronic wasting disease can be transmitted in the absence of animal-to-animal contact, and environmental reservoirs of infectivity have been implicated in their spread and persistence. Investigating environmental factors that influence the interaction of disease-associated PrP with soils is imperative to understanding what is likely to be the complex role of soil in disease transmission. Here, we describe the effects of soil temperature on the binding/desorption and persistence of both ovine scrapie- and bovine BSE-PrP (TSE) . Binding of PrP (TSE) to a sandy loam soil at temperatures of 4°C, 8-12°C and 25-30°C demonstrated that an increase in temperature resulted in (1) a decrease in the amount of PrP (TSE) recovered after 24 h of interaction with soil, (2) an increase in the amount of N-terminal cleavage of the prion protein over 11 d and (3) a decrease in the persistence of PrP (TSE) on soil over an 18 mo period.

References

Feb 2, 1991·Lancet·P Brown, D C Gajdusek
Nov 13, 1998·Proceedings of the National Academy of Sciences of the United States of America·S B Prusiner
Oct 22, 2002·The Journal of General Virology·Nora HunterFiona Houston
Jun 23, 2004·Emerging Infectious Diseases·Michael W MillerLisa L Wolfe
Dec 25, 2004·The Journal of Biological Chemistry·Cécile FéraudetJacques Grassi
Apr 18, 2006·PLoS Pathogens·Christopher J JohnsonJoel A Pedersen
Nov 14, 2006·The Journal of General Virology·Gudmundur GeorgssonPaul Brown
Apr 17, 2007·Molecular Biotechnology·Jonathan P OwenKevin C Gough
Jul 10, 2007·PLoS Pathogens·Christopher J JohnsonJudd M Aiken
Aug 9, 2008·Epidemiology and Infection·J E Truscott, N M Ferguson
Dec 6, 2008·Molecular Biotechnology·Helen C ReesKevin C Gough
Feb 27, 2009·Prion·Samuel E SaundersJason C Bartz
Mar 19, 2009·PloS One·Nicholas J HaleyEdward A Hoover
Apr 17, 2009·Environmental Science & Technology·Kurt H JacobsonJoel A Pedersen
Jun 6, 2009·Journal of Virology·B C MaddisonK C Gough
Aug 28, 2009·Environmental Science & Technology·Samuel E SaundersShannon L Bartelt-Hunt
Apr 21, 2010·The Journal of Infectious Diseases·Ben C MaddisonKevin C Gough
Aug 27, 2010·Journal of Virology·Ben C MaddisonKevin C Gough
Sep 14, 2010·Journal of Environmental Quality·Kurt H JacobsonJoel A Pedersen
Oct 26, 2010·Environmental Science & Technology·Ben C MaddisonKevin C Gough
Mar 25, 2011·Journal of Virology·Samuel E SaundersJason C Bartz
May 20, 2011·Veterinary Research·Linda A TerryKevin C Gough

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Citations

Feb 26, 2019·Archives of Virology·Robert A SomervilleNora Hunter
Jan 31, 2020·Food Safety·Susumu KumagaiTakashi Onodera

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