Temperature regulates hypoxia-inducible factor-1 (HIF-1) in a poikilothermic vertebrate, crucian carp (Carassius carassius)

The Journal of Experimental Biology
Eeva RissanenMikko Nikinmaa

Abstract

Hypoxia-inducible transcription factor-1 (HIF-1) is a master regulator of hypoxia-induced gene responses. To find out whether HIF-1 function is involved in gene expression changes associated with temperature acclimation as well as in hypoxia adaptation in poikilotherms, we studied HIF-1 DNA binding activity and HIF-1alpha expression in normoxia and during hypoxia (0.7 mg l(-1) O2) in crucian carp at temperatures of 26, 18 and 8 degrees C. Temperature had a marked influence on HIF-1 in normoxia. Although HIF-1alpha mRNA levels remained unaltered, cold acclimation (8 degrees C) increased HIF-1alpha protein amounts in the liver, gills and heart and HIF-1 DNA binding activity in the heart, gills and kidney of crucian carp by two- to threefold compared to warm acclimated fish (26 degrees C). In the heart and kidney HIF-1 activity was already significantly increased in the 18 degrees C acclimated fish. Temperature also affected hypoxic regulation of HIF-1. Although hypoxia initially increased amounts of HIF-1alpha protein in all studied tissues at every temperature, except for liver at 18 degrees C, HIF-1 activity increased only in the heart of 8 degrees C acclimated and in the gills of 18 degrees C acclimated fish. At 8 degrees C HI...Continue Reading

References

Jan 1, 1991·Annual Review of Physiology·S C Wood
Jan 1, 1995·Annual Review of Physiology·G N Somero
Aug 14, 1996·Biochemical and Biophysical Research Communications·C M WienerG L Semenza
Feb 1, 1997·Kidney International·R H WengerH H Marti
Feb 15, 2001·Proceedings of the National Academy of Sciences of the United States of America·A Y GraceyG N Somero
Apr 21, 2001·Molecular and Cellular Biology·T N SeagrovesR S Johnson
Jan 10, 2002·The Journal of Biological Chemistry·Dorthe M KatschinskiRoland H Wenger
Jun 8, 2002·The Journal of Biological Chemistry·Jennifer S IsaacsLeonard M Neckers
Aug 3, 2002·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Roland H Wenger
Sep 6, 2002·Biochemical Pharmacology·Gregg Semenza
Oct 11, 2002·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Amanda W WyattGiovanni E Mann
Oct 16, 2002·The Journal of Biological Chemistry·Elisabeth L PagéDarren E Richard
Aug 2, 2003·Biochemical and Biophysical Research Communications·Khaled Said AliEdit Hermesz
Aug 6, 2003·General and Comparative Endocrinology·Jean-Charles GabillardPierre-Yves Le Bail
Aug 21, 2003·General and Comparative Endocrinology·Jean-Charles GabillardPierre-Yves Le Bail
Sep 11, 2003·The Journal of Experimental Biology·Jørund SollidGöran E Nilsson
May 11, 2004·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Yan HuangFrank J Giordano
May 25, 2004·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Yaluan MaJoachim Fandrey
Jun 24, 2004·Proceedings of the National Academy of Sciences of the United States of America·Imad ShamsEviatar Nevo
Aug 21, 2004·Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology·Dörthe M KatschinskiRoland H Wenger
Aug 26, 2004·PLoS Biology·Steven D MasonRandall S Johnson
Nov 17, 2004·Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology·George N Somero
Nov 20, 2004·Proceedings of the National Academy of Sciences of the United States of America·Andrew Y GraceyAndrew R Cossins
Dec 25, 2004·The International Journal of Biochemistry & Cell Biology·Marc-André C DéryDarren E Richard
Nov 29, 2005·Molecular and Cellular Biochemistry·Pier MorinKenneth B Storey

❮ Previous
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Citations

Jun 21, 2007·Journal of Comparative Physiology. B, Biochemical, Systemic, and Environmental Physiology·K HeiseD Abele
Mar 29, 2011·Journal of Comparative Physiology. B, Biochemical, Systemic, and Environmental Physiology·Bradley A Buckley
Aug 21, 2013·Ecotoxicology and Environmental Safety·Elena De DomenicoSalvatore Fasulo
Jan 1, 2009·Annual Review of Marine Science·Denise L BreitburgRobert J Diaz
Nov 15, 2007·Theoretical Biology & Medical Modelling·María-Angeles AllerJaime Arias
Jan 8, 2013·Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology·John S CameronEsther Kang
Apr 17, 2014·Genetics, Selection, Evolution : GSE·Zhi-Gang Shen, Han-Ping Wang
Jul 18, 2014·Aquatic Toxicology·Amit Kumar SinhaGudrun De Boeck
Nov 15, 2014·Journal of Comparative Physiology. B, Biochemical, Systemic, and Environmental Physiology·Konstantinos FeidantsisBasile Michaelidis
Aug 1, 2012·Respiratory Physiology & Neurobiology·Göran E NilssonJonathan A W Stecyk
Jul 12, 2011·Physiological and Biochemical Zoology : PBZ·Jody M Beers, Bruce D Sidell
Dec 2, 2011·Comparative Biochemistry and Physiology. Part D, Genomics & Proteomics·Jonathan A W StecykGöran E Nilsson
Feb 14, 2012·Marine Genomics·Mikko Nikinmaa, Kalle T Rytkönen
Aug 20, 2011·Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology·Gillian M C RenshawShailendra Anoopkumar-Dukie
Dec 7, 2011·Aquatic Toxicology·Mikko Nikinmaa, Kalle T Rytkönen
Jul 10, 2010·Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology·Rui-Jie ShenShu-Ming Zou
Jul 11, 2009·Ageing Research Reviews·Olli ArjamaaKai Kaarniranta
Mar 7, 2013·Evolution; International Journal of Organic Evolution·Kalle T RytkönenMikko Nikinmaa
Mar 17, 2006·Respiratory Physiology & Neurobiology·Jørund Sollid, Göran E Nilsson
Mar 6, 2012·Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology·Amanda A SmithChris M Wood
Jan 5, 2014·Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology·Xin GengZhanjiang Liu

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