Temporal and spatial expression of Muc1 during implantation in sows.

International Journal of Molecular Sciences
Qian RenAiguo Wang

Abstract

Recent evidence points to an important role for Muc1 in embryo implantation. In this study, Real-time PCR and immunohistochemistry were used to study mRNA and protein levels at, and between, the attachment sites of the endometrium of Day 13, 18 and 24 pregnant sows. The results indicate that Muc1 mRNA expression was higher between attachment sites than at attachment sites during implantation and this effect was significant on Day 13 (P < 0.01) and 24 (P < 0.01). Intense Muc1 immunostaining was observed in luminal epithelium and stroma and the staining between attachment sites was stronger than at attachment sites on Days 13 and 18. Collectively, these results suggest the crucial role of Muc1 in successful implantation and embryo survival.

References

May 29, 1992·Biochemical and Biophysical Research Communications·L PembertonS J Gendler
Jan 1, 1986·Annals of the New York Academy of Sciences·A Psychoyos
Sep 1, 1985·Cell Differentiation·G R CunhaY Sugimura
Jan 1, 1985·Anatomy and Embryology·V Dantzer
Apr 1, 1981·Placenta·M GuillomotS Wintenberger-Torres
Aug 1, 1995·Endocrinology·G A SurveyorD D Carson
Jan 1, 1995·Annual Review of Physiology·S J Gendler, A P Spicer
Sep 2, 1998·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·D D CarsonE G Regisford
Feb 23, 1999·Human Reproduction Update·D D CarsonJ Julian
Aug 28, 1999·Human Reproduction Update·E LagowD D Carson
Feb 16, 2000·Journal of Reproductive Immunology·M M DeSouzaD D Carson
Feb 26, 2000·Human Reproduction·L C Giudice
Apr 15, 2000·Glycobiology·F G Hanisch, S Müller
Jul 7, 2000·Developmental Biology·D D CarsonK Yoshinaga
Feb 16, 2002·Methods : a Companion to Methods in Enzymology·K J Livak, T D Schmittgen
May 15, 2002·Reviews in Endocrine & Metabolic Disorders·Amantha Thathiah, Daniel D Carson
Dec 12, 2002·Cells, Tissues, Organs·Robert C BurghardtFuller W Bazer
May 22, 2003·Best Practice & Research. Clinical Obstetrics & Gynaecology·Andrew M Sharkey, Stephen K Smith
Jan 9, 2004·Reproductive Biology and Endocrinology : RB&E·Melissa BraymanDaniel D Carson
May 5, 2006·Reproduction : the Official Journal of the Society for the Study of Fertility·Etienne LordMarie-France Palin
Apr 19, 2007·Molecular Reproduction and Development·Haichao LinAiguo Wang
Jun 13, 2008·Nature Protocols·Thomas D Schmittgen, Kenneth J Livak

❮ Previous
Next ❯

Citations

Sep 7, 2012·Reproduction, Fertility, and Development·Sandra WilsherW R Allen
Sep 25, 2017·Reproduction, Fertility, and Development·Hitomi NakamuraTadashi Kimura
Jul 4, 2018·Journal of Cellular Physiology·Fahimeh Zamani RaraniBahman Rashidi
Aug 14, 2018·Reproduction in Domestic Animals = Zuchthygiene·Yanfeng FuShouwen Ren
Jun 14, 2013·Reproduction, Fertility, and Development·Wilasinee InyawilertPin-Chi Tang
Dec 19, 2017·International Journal of Veterinary Science and Medicine·Kabir A Raheem
Feb 14, 2012·Molecular Biology Reports·Chen XiaoWang Aiguo
Jun 10, 2011·Molecular Biology Reports·Yanfeng FuAiguo Wang

❮ Previous
Next ❯

Datasets Mentioned

BETA
AY243508

Methods Mentioned

BETA
biopsy
Scanning Electron Microscopy
Reverse Transcription Trizol
Polymerase Chain Reaction
PCR

Software Mentioned

Statistical Analysis
Quantity One

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.