Temporal changes in the tear menisci following a blink

Experimental Eye Research
Michael Edward Johnson, Paul James Murphy

Abstract

This study investigated tear meniscus formation after a blink. Multiple images of the inferior and superior menisci, viewed en-face, were sequentially captured using a video-slitlamp that permitted the measurement of tear meniscus height (TMH). In a similar manner, tangentially viewed images were obtained of the inferior meniscus so changes in cross-sectional radius of curvature (TMR) with time could be determined. Additionally, the relationship between inferior TMH and tear volume was quantified by the successive instillation of small aliquots of fluid. In this latter experiment the inflow and outflow of tears were controlled by anaesthetizing the ocular surface and inner nose, and use of punctal plugs. The TMH of both menisci rose after a blink (p<0.01) by a similar amount (p=0.59). This suggests that capillarity is dominant over gravity in tear drainage, however, it may simply reflect that these influences are small compared to the large flow resistances that occur in thin films, hydraulic connectivity between the two menisci, or differences in their anterior-posterior width leading to unequal volume-height relationships. TMR increased with time after a blink (p<0.0001); immediately on eye opening the curvature of the inferi...Continue Reading

References

Sep 1, 1977·Survey of Ophthalmology·F J Holly, M A Lemp
Jun 1, 1979·Archives of Ophthalmology·D W LambertsH D Perry
Nov 1, 1991·International Ophthalmology·J M Tiffany
Jun 1, 1991·Korean Journal of Ophthalmology : KJO·K J Lim, J H Lee
Jul 30, 1971·American Journal of Ophthalmology·J E McDonald, S Brubaker
Sep 1, 1980·Ophthalmology·A Jordan, J Baum
Jan 1, 1996·The British Journal of Ophthalmology·H FujishimaK Tsubota
Jun 1, 1996·Current Eye Research·J C MainstoneT R Golding
Dec 1, 1996·Journal of Colloid and Interface Science·H WongC J Radke
Jan 1, 1997·Optometry and Vision Science : Official Publication of the American Academy of Optometry·J P Craig, A Tomlinson
Dec 13, 1997·Cornea·A GuptaS C Pflugfelder
Dec 13, 1997·Cornea·T R GoldingJ C Mainstone
Dec 24, 1997·American Journal of Ophthalmology·A MoriK Tsubota
Mar 11, 1998·Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association for Ocular Pharmacology and Therapeutics·R D SchoenwaldC F Barfknecht
Apr 21, 1999·The British Journal of Ophthalmology·N YokoiC Fowler
Jun 12, 1999·The British Journal of Ophthalmology·W A van den BoschP Mulder
May 30, 2002·The British Journal of Ophthalmology·N Eter, M Göbbels
Jan 31, 2003·Investigative Ophthalmology & Visual Science·Eiki GotoKazuo Tsubota
Feb 28, 2003·Current Eye Research·Kimberly L MillerClayton J Radke
Mar 27, 2003·Cornea·Norihiko YokoiJohn M Tiffany
Sep 17, 2003·Mathematical Medicine and Biology : a Journal of the IMA·R J Braun, A D Fitt
Sep 1, 1961·Experimental Eye Research·S MISHIMA, D M MAURICE
Apr 27, 2004·Experimental Eye Research·A J BronL W Voon
May 25, 2004·Archives of Orthopaedic and Trauma Surgery·Kazuyoshi HiroseNaoki Ishiguro
Sep 15, 2004·Archives of Ophthalmology·Norihiko YokoiShigeru Kinoshita
Dec 14, 2004·Current Eye Research·P Ewen King-SmithJohn M Tiffany
Feb 5, 2005·Ophthalmology·Cat N Burkat, Mark J Lucarelli
Jul 15, 2005·Mathematical Medicine and Biology : a Journal of the IMA·M B JonesM J Collins
Dec 17, 2005·Optometry and Vision Science : Official Publication of the American Academy of Optometry·Michael Edward Johnson, Paul James Murphy
Apr 29, 2006·Experimental Eye Research·Michael E Johnson, Paul J Murphy
Nov 1, 2006·The Ocular Surface·James P McCulley, Ward E Shine
Nov 7, 2009·Investigative Ophthalmology & Visual Science·Vijaya K GothwalCharles W McMonnies
Feb 1, 2013·Contact Lens & Anterior Eye : the Journal of the British Contact Lens Association·Nathan EfronJinzhong Zhang

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Citations

May 1, 2012·Eye & Contact Lens·Jianhua LiFan Lu
Apr 9, 2013·Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie·Cheol KimSang In Khwarg
Jun 26, 2012·Survey of Ophthalmology·Samantha McGinnigleFrank Eperjesi
Feb 23, 2011·The Ocular Surface·Antonio A V CruzSheila P Cechetti
Jul 6, 2010·Nanomedicine : Nanotechnology, Biology, and Medicine·Santosh Khanal, Thomas J Millar
Aug 30, 2008·American Journal of Ophthalmology·Jayachandra R PalakuruJames V Aquavella
Mar 11, 2008·American Journal of Ophthalmology·Jianhua WangJames V Aquavella
Apr 10, 2010·American Journal of Ophthalmology·Yimin YuanMohamed Abou Shousha
Jun 6, 2015·The Ocular Surface·Heiko PultPaul J Murphy
Dec 1, 2009·Progress in Retinal and Eye Research·E A GaffneyA J Bron
Apr 29, 2006·Experimental Eye Research·Michael E Johnson, Paul J Murphy
Feb 22, 2017·Veterinary Ophthalmology·Hannah E VisserR David Whitley
Oct 17, 2017·Mathematical Medicine and Biology : a Journal of the IMA·Longfei LiP E King-Smith
Sep 14, 2011·International Archives of Allergy and Immunology·Krisztina Kosina-HagyóJános Németh
Sep 18, 2007·Optometry and Vision Science : Official Publication of the American Academy of Optometry·Etty BittonLyndon Jones
Aug 5, 2008·Optometry and Vision Science : Official Publication of the American Academy of Optometry·Wendy W HarrisonJanine A Smith
Jan 29, 2020·Mathematical Medicine and Biology : a Journal of the IMA·Kara L MakiGregory A Barron
Sep 4, 2019·Optometry and Vision Science : Official Publication of the American Academy of Optometry·Nur Amalina Md IsaPavithra Doraj
Jun 12, 2019·Translational Vision Science & Technology·Hung-Yin LaiIng-Chou Lai
Feb 10, 2021·Current Eye Research·José Vicente García-MarquésAlejandro Cerviño

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