Temporal information extraction from mental health records to identify duration of untreated psychosis.

Journal of Biomedical Semantics
Natalia VianiSumithra Velupillai

Abstract

Duration of untreated psychosis (DUP) is an important clinical construct in the field of mental health, as longer DUP can be associated with worse intervention outcomes. DUP estimation requires knowledge about when psychosis symptoms first started (symptom onset), and when psychosis treatment was initiated. Electronic health records (EHRs) represent a useful resource for retrospective clinical studies on DUP, but the core information underlying this construct is most likely to lie in free text, meaning it is not readily available for clinical research. Natural Language Processing (NLP) is a means to addressing this problem by automatically extracting relevant information in a structured form. As a first step, it is important to identify appropriate documents, i.e., those that are likely to include the information of interest. Next, temporal information extraction methods are needed to identify time references for early psychosis symptoms. This NLP challenge requires solving three different tasks: time expression extraction, symptom extraction, and temporal "linking". In this study, we focus on the first step, using two relevant EHR datasets. We applied a rule-based NLP system for time expression extraction that we had previousl...Continue Reading

References

Jul 4, 2006·The British Journal of Psychiatry : the Journal of Mental Science·Stephen KiselyGregory Simon
Jul 24, 2007·Schizophrenia Research·Julia M LappinRobin M Murray
Mar 8, 2013·Journal of the American Medical Informatics Association : JAMIA·Yan XuEric I-Chao Chang
Apr 6, 2013·Journal of the American Medical Informatics Association : JAMIA·Sunghwan SohnHongfang Liu
Apr 9, 2013·Journal of the American Medical Informatics Association : JAMIA·Weiyi SunOzlem Uzuner
Jul 12, 2013·BMC Medical Informatics and Decision Making·Andrea C FernandesFelicity Callard
Jul 23, 2013·Journal of Biomedical Informatics·Weiyi SunOzlem Uzuner
Apr 15, 2015·Journal of the American Medical Informatics Association : JAMIA·Weiyi SunOzlem Uzuner
Nov 23, 2017·Journal of Biomedical Informatics·Yanshan WangHongfang Liu

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Citations

Sep 9, 2020·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Robert Stewart, Sumithra Velupillai
Sep 4, 2021·Yearbook of Medical Informatics·Natalia GrabarUNKNOWN Section Editors of the IMIA Yearbook Section on Clinical Natural Language Processing

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Software Mentioned

System2
HeidelTime
SUTime
SUTime )
CRIS
TimeNorm
Clinical Record Interactive Search ( CRIS )
TimeML
THYME

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