PMID: 8614572Nov 17, 1995Paper

Temporal link between plasma thyrotropin levels and electroencephalographic activity in man

Neuroscience Letters
C GronfierG Brandenberger

Abstract

Plasma thyrotropin (TSH) levels have been previously shown to be associated with the internal sleep structure determined by conventional scoring of sleep stages. This temporal relationship was re-evaluated using spectral analysis of the sleep electroencephalogram (EEG). Eight healthy male subjects underwent two randomized night studies after having received either placebo or 5 mg ritanserin, a selective 5-HT2 receptor antagonist known to increase slow-wave sleep. Delta relative power and TSH levels, determined at 10 min intervals, were found to be inversely related with an average cross-correlation coefficient highly significant (P < 0.0001) in both experimental conditions. Alpha slow-wave index, an estimator of awakenings, and TSH pulses exhibited a significant temporal association in both conditions. These results demonstrate that TSH fluctuations are linked to the sleep EEG activity in man.

References

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Citations

May 30, 2001·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·G BrandenbergerC Simon
May 25, 2013·Endocrinology and Metabolism Clinics of North America·Georges Copinschi, Anne Caufriez
Sep 24, 2011·Molecular and Cellular Endocrinology·Christopher J MorrisFrank A J L Scheer
Mar 19, 2013·Journal of Sleep Research·Sebastian M SchmidBernd Schultes
Jan 29, 2014·Medical Hypotheses·José Carlos Pereira, Mônica Levy Andersen
Apr 11, 2015·International Journal of Endocrinology·Tae Won KimSeung-Chul Hong
Oct 25, 2016·Scientific Reports·Shingo KitamuraKazuo Mishima
Oct 3, 2015·PloS One·Eirini KallioliaThomas T Warner
Aug 18, 2004·Sleep Medicine Reviews·C Gronfier, G Brandenberger
Apr 12, 2013·Endocrine Reviews·Ferdinand Roelfsema, Johannes D Veldhuis
Aug 12, 1999·The Journal of Clinical Endocrinology and Metabolism·C GronfierG Brandenberger
Dec 11, 2017·Best Practice & Research. Clinical Endocrinology & Metabolism·Ferdinand RoelfsemaEric Fliers

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