Temporal precision of the encoding of motion information by visual interneurons

Current Biology : CB
A-K WarzechaM Egelhaaf

Abstract

There is much controversy about the timescale on which neurons process and transmit information. On the one hand, a vast amount of information can be processed by the nervous system if the precise timing of individual spikes on a millisecond timescale is important. On the other hand, neuronal responses to identical stimuli often vary considerably and stochastic response fluctuations can exceed the mean response amplitude. Here, we examined the timescale on which neural responses could be locked to visual motion stimuli. Spikes of motion-sensitive neurons in the visual system of the blowfly are time-locked to visual motion with a precision in the range of several tens of milliseconds. Nevertheless, different motion-sensitive neurons with largely overlapping receptive fields generate a large proportion of spikes almost synchronously. This precision is brought about by stochastic rather than by motion-induced membrane-potential fluctuations elicited by the common peripheral input. The stochastic membrane-potential fluctuations contain more power at frequencies above 30-40 Hz than the motion-induced potential changes. A model of spike generation indicates that such fast membrane-potential changes are a major determinant of the prec...Continue Reading

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Citations

Aug 14, 2001·Journal of Cellular Biochemistry·A M MartelliR Bortul
Jan 9, 2008·Biological cybernetics·Jens Peter LindemannMartin Egelhaaf
Sep 24, 1999·Vision Research·R A HarrisS B Laughlin
Jan 30, 2002·Trends in Neurosciences·Martin EgelhaafAnne Kathrin Warzecha
Jun 25, 2002·Neural Computation·P H E TiesingaTerrence J Sejnowski
Jan 16, 1999·Current Biology : CB·S B Laughlin
Nov 28, 2012·Journal of Physiology, Paris·Anne-Kathrin WarzechaJan Grewe
Jul 11, 2000·The European Journal of Neuroscience·W HorstmannA K Warzecha
May 15, 2002·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·P H E Tiesinga
Oct 16, 2015·Journal of Mathematical Neuroscience·Sergej O VoronenkoBenjamin Lindner
Jul 20, 2010·The Journal of Experimental Biology·Peter J Simmons, Rob R de Ruyter van Steveninck
Mar 31, 2009·The Journal of Experimental Biology·R RosnerA K Warzecha
Mar 19, 1999·Science·A K Warzecha, M Egelhaaf

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