Temporal resolution of idiopathic granulomatous mastitis with resumption of bromocriptine therapy for prolactinoma

International Journal of Surgery Case Reports
Marcia E BoutonIan K Komenaka

Abstract

Idiopathic granulomatous mastitis (IGM) is becoming more commonly recognized and reported more often. Currently, many recommend corticosteroids in its management. A 34-year-old G3P2 Hispanic female, 28 weeks pregnant, presented with a 19cm right breast mass. She had a known prolactinoma treated with bromocriptine which was discontinued during her pregnancy. Ultrasound guided core biopsy procedure revealed granulomatous mastitis. The patient was told that the mass would resolve with observation. The patient seen at another institution by an infectious disease specialist who started treatment with amphotericin for presumptive disseminated coccidioidomycosis. Repeated titers were negative for coccidioides antibody. Repeat cultures were negative as well. Due to the persistence of the infectious disease specialist, tissue cultures were performed on fresh tissue specimens, which did not grow bacterial, fungal, nor acid fast organisms. The amphotericin regimen resulted in no improvement of her breast mass after 10 weeks. Within two weeks of stopping the antifungal therapy, however, the mass diminished to 6cm. The patient delivered at 39 weeks. Bromocriptine was restarted, and within 4 weeks, the lesion was no longer palpable. She had ...Continue Reading

References

Apr 20, 1995·The New England Journal of Medicine·D A Stevens
Nov 25, 1998·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·E L ArsuraS N Ratnayake
Jun 19, 2004·Pathology·Gary M K TseHumairah S Cheung
Jul 9, 2004·The Breast Journal·Kamal E Bani-HaniNawaf J Shatnawi
Sep 1, 2007·The Breast Journal·Ricka TaghizadehEva M Weiler-Mithoff
Jan 29, 2008·Journal of the American College of Surgeons·Bilal Al-KhaffafNigel J Bundred
Jun 24, 2010·The Surgeon : Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland·K Y Y Kok, P U Telisinghe
Aug 5, 2011·Journal of Plastic, Reconstructive & Aesthetic Surgery : JPRAS·Michaela HladikGottfried Wechselberger
Jul 11, 2014·Annals of Surgical Oncology·Kathie-Ann JosephAdam Mor

❮ Previous
Next ❯

Citations

Jul 28, 2017·ANZ Journal of Surgery·Erdal UysalUNKNOWN Granulomatous Mastitis Study Group

❮ Previous
Next ❯

Methods Mentioned

BETA
biopsy
PCR

Related Concepts

Related Feeds

Antifungals

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.

Antifungals (ASM)

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.

Related Papers

American Journal of Surgery
Marcia E BoutonIan K Komenaka
American Journal of Therapeutics
Kashmira WankhedkarRobert Lahita
United States Armed Forces Medical Journal
R C HUNTER, E S MONGAN
© 2021 Meta ULC. All rights reserved