PMID: 489844Sep 1, 1979Paper

Temporal summation of pulsate brain stimulation in normal and deafened cats

The Journal of the Acoustical Society of America
G M Gerken

Abstract

Behaviorally measured, electrical-stimulation thresholds were obtained from 11 electrodes permanently positioned in the auditory system and other brain loci. Number of pulses and interpulse intervals were varied to determine how detection thresholds were affected by stimulation parameters. Detection thresholds generally decreased with increased number of pulses and with shorter interpulse intervals. A method is presented to describe the parametric threshold data for each electrode in terms of three constants: a single-pulse threshold which characterizes the sensitivity of the placement; a time constant of temporal summation; and a compression factor which describes the range of threshold variation. For three placements in the vicinity of cochlear nucleus, bilateral cochlear destruction permanently altered parametric thresholds. In particular, single-pulse threshold was lowered by 9.2 dB; time constant of temporal summation was reduced by a factor of 100; and the compression factor was increased. Classic strength-duration time constants were determined using behavioral methods and were shown to be equal in magnitude to the greatly reduced time constants for temporal summation in the deafened animals. This implies that capacity f...Continue Reading

Citations

Jan 1, 1983·Hearing Research·J A Costalupes
May 9, 2002·International Journal of Pediatric Otorhinolaryngology·Erica D Fielding, Vishakha W Rawool
Jan 10, 2012·The Journal of the Acoustical Society of America·Bryan E PfingstGina L Su
Feb 4, 2006·The Journal of the Acoustical Society of America·Ray Meddis
Jun 2, 2005·Journal of Neuroscience Research·Mikiya AsakoRichard A Altschuler
Jul 1, 1996·Audiology : Official Organ of the International Society of Audiology·V W Rawool

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