Temporal trends and black-white disparity in mortality among hospitalized persons living with HIV in the United States

Medicine
Hamisu M SalihuMuktar H Aliyu

Abstract

We sought to determine whether black-white gap in mortality exists among hospitalized HIV-positive patients in the United States (US). We hypothesized that in-hospital mortality (IHM) would be similar between black and white HIV-positive patients due to the nationwide availability of HIV services.Our analysis was restricted to hospitalized HIV-positive patients (15-49 years). We used the National Inpatient Sample (NIS) that covered the period from January 1, 2002 to December 31, 2014. We employed joinpoint regression to construct temporal trends in IHM overall and within subgroups over the study period. We applied multivariable survey logistic regression to generate adjusted odds ratios (OR) and 95% confidence intervals (CI).The total number of HIV-related hospitalizations and IHM decreased over time, with 6914 (3.9%) HIV-related in-hospital deaths in 2002 versus 2070 HIV-related in-hospital deaths (1.9%) in 2014, (relative reduction: 51.2%). HIV-related IHM among blacks declined at a slightly faster rate than in the general population (by 56.8%, from 4.4% to 1.9%). Among whites, the drop was similar to that of the general population (51.2%, from 3.9% to 1.9%). Although IHM rates did not differ between blacks and whites, being ...Continue Reading

References

Jan 29, 2000·Statistics in Medicine·H J KimD N Midthune
Apr 9, 2009·Biodemography and Social Biology·Isaac W EbersteinKathleen M Heyman
Jun 18, 2009·Current Opinion in HIV and AIDS·Mark A Boyd
Sep 24, 2009·International Journal of Epidemiology·Marcel Zwahlen
Oct 13, 2009·International Journal of Epidemiology·UNKNOWN Antiretroviral Therapy Cohort CollaborationMatthias Egger
Apr 21, 2010·American Journal of Public Health·Marcie S RubinBruce G Link
Jan 20, 2011·The Journal of Infectious Diseases·Amie L MeditzElizabeth Connick
Mar 4, 2011·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Edward M GardnerWilliam J Burman
Jul 24, 2012·JAMA : the Journal of the American Medical Association·Melanie A ThompsonPaul A Volberding
Jan 15, 2013·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·David B HannaUNKNOWN North American AIDS Cohort Collaboration on Research and Design (NA-ACCORD) of the International Epidemiologic Databases to
Jun 6, 2013·Advances in Preventive Medicine·Gopal K SinghMohammad Siahpush
Dec 25, 2013·PloS One·Hasina SamjiUNKNOWN North American AIDS Cohort Collaboration on Research and Design (NA-ACCORD) of IeDEA
Feb 21, 2016·Journal of Racial and Ethnic Health Disparities·Kristi L AllgoodMonique Glover Rucker

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