Abstract
Peritonitis remains a common complication of peritoneal dialysis (PD). The aim of this study was to analyze, in a PD center, long-term temporal trends in peritonitis rates, microbiology and outcomes. We treated 588 cases of peritonitis that occurred during 11,833.6 months at risk. Y-set and twin-bag disconnecting systems were introduced in 1990, mupirocin at the exit site in 2000 and fluconazole prophylaxis in 2005. Vancomycin and ceftazidime were the empiric protocol. Global and 5-year cohort rates were expressed as episodes/patient-year (ep/p-y). A global peritonitis rate reduction was found from 1.02 to 0.47 ep/p-y (p = 0.008). Poisson analyses performed in each of the subgroups of Gram-positive and Gram-negative peritonitis revealed no significant changes over time. No case of vancomycin resistance was identified. There was a downward trend in peritonitis-related hospitalization over time to 0.11 ep/p-y (p ≤ 0.001). Trend analysis showed a favorable, but changing evolution, highlighting the importance of accurate longitudinal PD center registry data and quality control.
References
Jan 3, 2001·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·J M Duch, J Yee
May 31, 2001·Kidney International·C C SzetoP K Li
Dec 31, 2004·Journal of the American Society of Nephrology : JASN·Judith BernardiniBeth Piraino
Feb 3, 2005·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Than N OoAllan J Collins
Sep 29, 2006·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Ashutosh ShuklaJoanne M Bargman
Jan 16, 2007·The International Journal of Artificial Organs·A S RodriguesA Cabrita
Aug 21, 2007·Clinical Journal of the American Society of Nephrology : CJASN·Cheuk-Chun SzetoPhilip Kam-Tao Li
Jan 16, 2009·Diabetes/metabolism Research and Reviews·S BoG Pagano
May 2, 2009·Clinical Journal of the American Society of Nephrology : CJASN·Brian SivaDavid W Johnson
Jun 12, 2009·Kidney International·Rhianna MilesDavid W Johnson
Nov 26, 2009·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Katherine BarracloughDavid W Johnson
Jan 30, 2010·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Magid FahimDavid W Johnson
Feb 4, 2010·Peritoneal Dialysis International : Journal of the International Society for Peritoneal Dialysis·Inna KolesnykRaymond T Krediet
Mar 27, 2010·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Sandra BrumAntónio Cabrita
May 15, 2010·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Magid FahimDavid W Johnson
May 28, 2010·Kidney International·Elizabeth M JarvisDavid W Johnson
Jul 16, 2010·Peritoneal Dialysis International : Journal of the International Society for Peritoneal Dialysis·Philip Kam-Tao LiUNKNOWN International Society for Peritoneal Dialysis
Sep 30, 2010·Archives of Internal Medicine·Rajnish MehrotraEdward Vonesh
Dec 24, 2010·Nephrology·Matthew D JoseKym M Bannister
May 6, 2011·Clinical Nephrology·S-T HuangK-H Shu
Citations
Sep 4, 2013·Biofouling·Margarida MartinsRosário Oliveira
Apr 23, 2014·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Yeoungjee Cho, David W Johnson
Feb 26, 2016·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Lei ZhangDavid W Johnson
Oct 16, 2015·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Danilo LofaroJaap W Groothoff
Dec 24, 2009·BMC Infectious Diseases·Pasqual BarrettiMaria de Lourdes R S Cunha
Sep 3, 2014·American Journal of Infection Control·Anabela RodriguesMargarida Martins
Nov 2, 2016·Journal of the American Society of Nephrology : JASN·Rajnish MehrotraDavid W Johnson
Jan 31, 2012·Infectious Disease Clinics of North America·Natasha BagdasarianPreeti N Malani
Jun 24, 2016·PloS One·Joana SampaioMargarida Martins
Feb 6, 2017·Seminars in Nephrology·Yeoungjee Cho, Dirk Gijsbert Struijk
Oct 9, 2014·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Denise J CampbellJonathan C Craig
Aug 1, 2015·Peritoneal Dialysis International : Journal of the International Society for Peritoneal Dialysis·Lei ZhangUNKNOWN HONEYPOT Study Collaborative Group
Sep 24, 2016·Peritoneal Dialysis International : Journal of the International Society for Peritoneal Dialysis·Liliana Simões-SilvaBenedita Sampaio-Maia
Jun 11, 2016·Peritoneal Dialysis International : Journal of the International Society for Peritoneal Dialysis·Philip Kam-Tao LiDavid W Johnson
Aug 13, 2020·Renal Failure·Ying ZengShan Jiang
Aug 16, 2017·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Wim Van Biesen, Edwina A Brown
Sep 4, 2018·The Canadian Journal of Infectious Diseases & Medical Microbiology = Journal Canadien Des Maladies Infectieuses Et De La Microbiologie Médicale·Liliana Simões-SilvaBenedita Sampaio-Maia
Jul 11, 2020·Journal of Nephrology·Luca NardelliPiergiorgio Messa
Dec 22, 2020·PloS One·Joana Eugénio SantosMiguel Pérez Fontán
Jan 5, 2021·World Journal of Clinical Cases·Bin-Bin DaiYang-Bin Pan
May 11, 2013·The International Journal of Artificial Organs·Karina LopesAntónio Cabrita