Temporal trends in receipt of adequate lymphadenectomy in bladder cancer 1988 to 2010

Urologic Oncology
Alexander P ColeQuoc-Dien Trinh

Abstract

The importance of pelvic lymphadenectomy (LND) for diagnostic and therapeutic purposes at the time of radical cystectomy (RC) for bladder cancer is well documented. Although some debate remains on the optimal number of lymph nodes removed, 10 nodes has been proposed as constituting an adequate LND. We used data from the Surveillance, Epidemiology, and End Results database to examine predictors and temporal trends in the receipt of an adequate LND at the time of RC for bladder cancer. Within the Surveillance, Epidemiology, and End Results database, we extracted data on all patients with nonmetastatic bladder cancer receiving RC in the years 1988 to 2010. First, we assess the proportion of individuals undergoing RC who received an adequate LND (≥10 nodes removed) over time. Second, we calculate odds ratios (ORs) of receiving an adequate LND using logistic regression modeling to compare study periods. Covariates included sex, race, age, region, tumor stage, urban vs. rural location, and insurance status. Among the 5,696 individuals receiving RC during the years 1988 to 2010, 2,576 (45.2%) received an adequate LND. Over the study period, the proportion of individuals receiving an adequate LND increased from 26.4% to 61.3%. The odds...Continue Reading

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Citations

Jun 2, 2017·Current Opinion in Urology·Alexander P Cole, Quoc-Dien Trinh
Oct 24, 2018·Frontiers in Surgery·Francesco CattaneoFabrizio Dal Moro
Mar 17, 2016·The International Journal of Biological Markers·Chen-Min SunXu-Dong Yao
Jun 23, 2020·Oncology Letters·Keyi WangBo Peng
Dec 25, 2017·International Urology and Nephrology·Mahir MarufPiyush K Agarwal

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