Temporal trends in revascularization strategy and outcomes in left main coronary artery stenosis: data from the ASAN Medical Center-Left MAIN Revascularization registry

Circulation. Cardiovascular Interventions
Seung-Jung ParkSeong-Wook Park

Abstract

Changes over time in revascularization strategies and outcomes among patients with unprotected left main coronary artery stenosis remain largely unknown. A total of 2618 consecutive patients with unprotected left main coronary artery stenosis who underwent revascularization were identified from the ASAN Medical Center-Left MAIN Revascularization registry and classified by time periods: bare metal stent (wave 1, 1995-1998), early drug-eluting stents (wave 2, 2003-2006), and late drug-eluting stents (wave 3, 2007-2010). Primary end point was major adverse cerebrocardiovascular events (the composite of death, myocardial infarction, repeat revascularization, and stroke). During the study period, 1124 patients underwent percutaneous coronary intervention (PCI) and 1494 patients underwent coronary artery bypass grafting. The proportion of PCI significantly increased from 35% to 52% between waves 1 and 3. In patients receiving PCI, the risk-adjusted incidence rate of major adverse cerebro-cardiovascular events decreased from 20.18 cases per 100 person-years in wave 1 to 6.77 cases per 100 person-years in wave 3 (P<0.001 for trend). Death, the composite of death, myocardial infarction, stroke, and repeat revascularization were also sig...Continue Reading

References

Oct 24, 2006·The American Journal of Cardiology·George D GiannoglouGeorge E Louridas
Apr 2, 2008·The New England Journal of Medicine·Ki Bae SeungSeung-Jung Park
Aug 25, 2009·Journal of the American College of Cardiology·Pawel E BuszmanMichał Tendera
Sep 2, 2009·European Heart Journal·Gilles MontalescotUNKNOWN GRACE Investigators
Jul 16, 2010·JACC. Cardiovascular Interventions·Sanjay B PandyaNirat Beohar
Aug 31, 2010·European Heart Journal·UNKNOWN Task Force on Myocardial Revascularization of the European Society of Cardiology (ESC) and the European Association for CardDavid Taggart
Jan 13, 2011·JAMA : the Journal of the American Medical Association·Steven GoldmanKelvin Lee
Apr 6, 2011·The New England Journal of Medicine·Seung-Jung ParkKi Bae Seung
Apr 27, 2011·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Won-Jang KimSeung-Jung Park
Aug 28, 2012·Circulation·Kristian ThygesenShanti Mendis
Mar 13, 2013·The New England Journal of Medicine·André LamyUNKNOWN CORONARY Investigators

❮ Previous
Next ❯

Citations

Feb 20, 2016·JACC. Cardiovascular Interventions·Jung-Min Ahn, Seung-Jung Park
May 23, 2015·Journal of the American College of Cardiology·Joseph F Sabik, Gregg W Stone
May 14, 2016·EuroIntervention : Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology·Jens Flensted LassenGoran Stankovic
Jul 6, 2016·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·Georg FuernauHolger Thiele
Aug 16, 2016·International Journal of Cardiology·Naoki MisumidaYumiko Kanei
Sep 3, 2016·Journal of the American College of Cardiology·Rafael CavalcantePatrick W Serruys
Sep 10, 2016·Journal of the American College of Cardiology·Pil Hyung LeeSeung-Jung Park
Nov 1, 2016·The New England Journal of Medicine·Eugene Braunwald
Jan 24, 2018·Scandinavian Cardiovascular Journal : SCJ·Thomas GripenbergJonas Persson
Aug 5, 2017·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·Se Hun KangSeung-Jung Park
Mar 7, 2015·Circulation. Cardiovascular Interventions·Gregg W Stone
Dec 21, 2017·Texas Heart Institute Journal·Iñigo LozanoEduardo Segovia
May 6, 2017·JACC. Cardiovascular Interventions·Tanveer RabShao Liang Chen

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

© 2022 Meta ULC. All rights reserved