Temporal trends of polybrominated diphenyl ethers and hexabromocyclododecane in milk from Stockholm mothers, 1980-2004

Molecular Nutrition & Food Research
Britta FängströmAke Bergman

Abstract

Environmental and human exposures to brominated flame retardants (BFR) have been of emerging concern since some BFR are persistent and bioaccumulative compounds. Among those, polybrominated diphenyl ethers (PBDE) have frequently been reported in low to high ng/g concentrations in human blood around the world while hexabromocyclododecane (HBCDD) only occasionally has been reported and then in the low ppb concentrations in human blood. The present study concerns PBDE congener and HBCDD concentrations in human milk from Stockholm from 1980 to 2004. HBCDD concentrations has increased four to five times since 1980 until 2002 but seems to have stabilized at this concentration in the last years (2003/04). Similarly, BDE-153 has continued to increase at least to 2001, after which it has stabilized in the mother's milk. Other PBDE congeners with four to five bromine substituents peaked 5 years earlier (1995) and are all decreasing. DecaBDE (BDE-209) is not a suitable biomarker for time trend studies according to the present results, showing no changes over time. This is likely due to its short apparent half-life in humans and poor transfer from blood to milk.

References

Dec 2, 1999·Journal of Toxicology and Environmental Health. Part a·D MeironytéA Bergman
Dec 8, 2000·Journal of Analytical Toxicology·L HovanderE K Wehler
Aug 29, 2001·Journal of Environmental Monitoring : JEM·C ThomsenG Becher
Aug 30, 2001·Archives of Environmental Contamination and Toxicology·D Meironyté GuveniusK Norén
Sep 10, 2003·Environmental Research·Ylva LindAnders Glynn
Oct 16, 2003·Chemosphere·Mikael RembergerEva Brorström-Lundén
Nov 5, 2003·Environmental Health Perspectives·Arnold SchecterRobin Rosen
Dec 31, 2003·Environmental Health Perspectives·Linda S Birnbaum, Daniele F Staskal
Jul 15, 2005·Environmental Health : a Global Access Science Source·Britta FängströmAke Bergman
Aug 2, 2005·Environmental Science & Technology·Robin J LawCathrine Thomsen
Aug 9, 2005·Environmental Science & Technology·Boris Johnson-RestrepoBruce D Rodan
Jan 26, 2006·Chemosphere·Robin J LawCynthia A de Wit
Feb 7, 2006·Chemosphere·Cynthia A de WitDerek C G Muir
Jul 13, 2006·Environmental Science & Technology·Adrian CovaciJacob De Boer
Dec 13, 2006·Journal of Chromatography. a·Adrian CovaciRonny Blust
Feb 22, 2007·Environmental Science & Technology·Amelie KierkegaardKevin C Jones
Apr 17, 2007·Chemosphere·Leisa-Maree L TomsJochen F Müller

❮ Previous
Next ❯

Citations

Jan 6, 2011·Environmental Health : a Global Access Science Source·Irva Hertz-PicciottoDeborah H Bennett
Jul 13, 2012·Environmental Health : a Global Access Science Source·Solveig RavnumMartin Krayer von Krauss
Oct 12, 2012·Environmental Health Perspectives·Mireia GasconMartine Vrijheid
Jan 18, 2014·Archives of Environmental Contamination and Toxicology·Katrin VorkampTina Kold Jensen
Dec 3, 2014·Environment International·Jan L LycheAnuschka Polder
Mar 1, 2016·Environmental Pollution·Mandana BarghiYoon-Seok Chang
Jul 4, 2012·Chemosphere·Leisa-Maree L TomsJochen F Mueller
Dec 24, 2011·International Journal of Hygiene and Environmental Health·Bernhard LinkG Fischer
Mar 29, 2011·International Journal of Hygiene and Environmental Health·Lesa L Aylward, Sean M Hays
Jul 9, 2010·Environment International·Katrin VorkampLisbeth E Knudsen
May 18, 2010·International Journal of Hygiene and Environmental Health·Marie FrederiksenLisbeth E Knudsen
Apr 20, 2010·Environment International·Laurence RoosensAdrian Covaci
Nov 26, 2009·Environment International·Chang'er ChenLinke Ge
Nov 6, 2009·Environment International·Cathrine ThomsenMerete Eggesbø
May 26, 2009·International Journal of Developmental Neuroscience : the Official Journal of the International Society for Developmental Neuroscience·Henrik Viberg
Mar 10, 2009·Chemosphere·Iván N Pérez-MaldonadoFernando Díaz-Barriga
Sep 13, 2008·Chemosphere·Anna ChristianssonAke Bergman
Sep 8, 2015·Neurotoxicology and Teratology·Whitney J CowellJulie B Herbstman
Jul 12, 2008·Molecular Nutrition & Food Research·Michael HabermeyerGerhard Eisenbrand
Sep 2, 2009·Mass Spectrometry Reviews·Dongli Wang, Qing X Li
Dec 10, 2013·Paediatric and Perinatal Epidemiology·Margaret A AdgentJulie L Daniels
Sep 29, 2015·International Journal of Hygiene and Environmental Health·H FrommeW Völkel
Oct 1, 2015·Environmental Health : a Global Access Science Source·Panu RantakokkoJussi Pihlajamäki
Apr 9, 2015·International Journal of Hygiene and Environmental Health·Leena M O SahlströmPer Ola Darnerud
Apr 29, 2015·Environmental Science and Pollution Research International·Johan FångÅke Bergman

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.