Temporally coordinated signals progressively pattern the anteroposterior and dorsoventral body axes

Seminars in Cell & Developmental Biology
Francesca B Tuazon, M Mullins

Abstract

The vertebrate body plan is established through the precise spatiotemporal coordination of morphogen signaling pathways that pattern the anteroposterior (AP) and dorsoventral (DV) axes. Patterning along the AP axis is directed by posteriorizing signals Wnt, fibroblast growth factor (FGF), Nodal, and retinoic acid (RA), while patterning along the DV axis is directed by bone morphogenetic proteins (BMP) ventralizing signals. This review addresses the current understanding of how Wnt, FGF, RA and BMP pattern distinct AP and DV cell fates during early development and how their signaling mechanisms are coordinated to concomitantly pattern AP and DV tissues.

References

Feb 20, 2016·Nature Reviews. Endocrinology·Valerie S SalazarVicki Rosen
Nov 7, 2015·Wiley Interdisciplinary Reviews. Developmental Biology·Clémence Carron, De-Li Shi
May 25, 2015·Seminars in Cell & Developmental Biology·A J Durston
Nov 9, 2016·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·A Richard Palmer
Jul 13, 2017·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·A J Durston, Kongju Zhu
Jun 11, 2017·Cold Spring Harbor Perspectives in Biology·Joseph ZinskiM Mullins
Apr 3, 2019·EMBO Reports·Hanna PolevoyDale Frank
Feb 8, 2020·Journal of Computational Biology : a Journal of Computational Molecular Cell Biology·Yue WangNadya Morozova
Aug 11, 2019·Developmental Dynamics : an Official Publication of the American Association of Anatomists·Sheila Cardeña-NúñezMatías Hidalgo-Sánchez
Aug 22, 2017·Frontiers in Neuroanatomy·Holly C GibbsArne C Lekven
Oct 21, 2018·International Journal of Molecular Sciences·Anna Schliermann, Joachim Nickel
Feb 9, 2019·Scientific Reports·R RichardsonM Moosajee
Nov 28, 2019·Journal of Mathematical Biology·Linlin LiDavid M Umulis

Citations

Oct 1, 1969·Journal of Theoretical Biology·L Wolpert
Jan 1, 1995·Developmental Genetics·A Hemmati-Brivanlou, G H Thomsen
Jul 1, 1995·Current Biology : CB·A S Tucker, J M Slack
Dec 1, 1994·Mechanisms of Development·Y LiE S Weinberg
Mar 7, 1996·Nature·E M De Robertis, Y Sasai
Apr 1, 1997·Mechanisms of Development·A FainsodM Blum
Jan 27, 1998·Developmental Biology·V E Miller-BertoglioM E Halpern
Mar 5, 1998·Mechanisms of Development·L L McGrewR T Moon
Aug 26, 1998·Proceedings of the National Academy of Sciences of the United States of America·M R RebagliatiI B Dawid
Dec 11, 1999·Developmental Dynamics : an Official Publication of the American Association of Anatomists·A DickM Hammerschmidt
Jan 22, 2000·Developmental Biology·M TrindadeJ C Smith
Jul 13, 2000·Current Opinion in Genetics & Development·D Kimelman, K J Griffin
Aug 6, 2000·Developmental Biology·A E MelbyD Kimelman
Aug 31, 2000·Developmental Biology·M C Lane, M D Sheets
Oct 26, 2000·Proceedings of the National Academy of Sciences of the United States of America·A KawaharaI B Dawid
Dec 22, 2000·Genes & Development·E M GonzalezLilianna Solnica-Krezel
Jan 3, 2001·Developmental Biology·A Perz-EdwardsE Linney
Feb 13, 2001·Mechanisms of Development·L GrotewoldU Rüther
Jun 22, 2001·Nature·J BrennanE J Robertson
Jul 13, 2001·Current Opinion in Genetics & Development·A F Schier
Sep 13, 2001·Current Biology : CB·T P Yamaguchi
Jan 11, 2002·Developmental Biology·C W BeckJ M Slack
Feb 16, 2002·Developmental Biology·Dina C MyersLilianna Solnica-Krezel

Related Concepts

Vertebrates
NOG gene
Embryo
Establishment and Maintenance of Localization
Dorsoventral
Vitamin A
Biochemical Pathway
Cell Movement
HSPA4
Patterns

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