Temporary Wettability Tuning of PCL/PDMS Micro Pattern Using the Plasma Treatments

Materials
Wei-Chih Lin, Nur Adila Mohd Razali

Abstract

Surface wettability plays an important role in determining the function of a wound dressing. Dressings with hydrophobic surfaces are suitable for bacterial adsorption, however, a hydrophilic surface is needed to improve cell attachment for most anchorage-dependent cell types. Furthermore, the hydrophobicity/hydrophilicity of the surface can be used to direct cellular processes such as cell initial attachment, adhesion, and migration during wound healing. Thus, a surface with an ability to switch their surface wettability improves the practicality of the dressing. In this study, we propose a temporary surface wettability tuning for surface patterning utilizing plasma treatment. Polycaprolactone (PCL) and polydimethylsiloxane (PDMS) surfaces were treated with tetrafluoromethane (CF₄), sulphur hexafluoride (SF₆), and oxygen (O₂) plasma, and the effects on the surface wettability, roughness, and chemical composition were investigated. Based on the contact angle measurement, CF₄ plasma altered surface wettability of PCL and PDMS films to hydrophobic and hydrophilic, respectively. After CF₄ treatment, better attachment of primary mouse embryonic fibroblast cell (3T3) was observed on the treated PDMS surface. Embedding PCL into PDMS g...Continue Reading

References

May 19, 2000·Microbes and Infection·R J Doyle
Dec 8, 2005·Journal of Controlled Release : Official Journal of the Controlled Release Society·Koichiro UtoTakao Aoyagi
Mar 18, 2006·Biomedical Research·Masao YoshinariTeruo Tanaka
Jun 23, 2010·Journal of Biomaterials Applications·Denis P DowlingWilliam M Gallagher
Jun 29, 2010·Progress in Polymer Science·Vince Beachley, Xuejun Wen
Sep 29, 2011·Advanced Materials·Mitsuhiro EbaraTakao Aoyagi
Dec 1, 2011·Electrophoresis·Jinwen ZhouNicolas H Voelcker
Nov 6, 2013·Carbohydrate Polymers·Abdelrahman M AbdelgawadOrlando J Rojas
Sep 4, 2015·Journal of Nanoscience and Nanotechnology·Yeong-Mu KoByung-Hoon Kim
Apr 14, 2016·Journal of Physics. Condensed Matter : an Institute of Physics Journal·Anh Tuan NguyenEvelyn K F Yim
Apr 24, 2018·Journal of Colloid and Interface Science·Alessandro F MartinsMatt J Kipper
Sep 5, 2017·Polymers·Lan Thi PhanMyoung-Woon Moon

❮ Previous
Next ❯

Citations

May 16, 2020·Materials Science & Engineering. C, Materials for Biological Applications·Antonios KeirouzNorbert Radacsi
Sep 4, 2021·Materials Science & Engineering. C, Materials for Biological Applications·Nur Adila Mohd RazaliZhi-Wei Yu

❮ Previous
Next ❯

Methods Mentioned

BETA
biosensors
X-Ray
AFM
fluorescence microscopy

Software Mentioned

ImageJ
FAMAS Basic

Related Concepts

Related Feeds

Cell Migration

Cell migration is involved in a variety of physiological and pathological processes such as embryonic development, cancer metastasis, blood vessel formation and remoulding, tissue regeneration, immune surveillance and inflammation. Here is the latest research.

Biophysics of Adhesion

Alterations in cell adhesion can disrupt important cellular processes and lead to a variety of diseases, including cancer and arthritis. It is also essential for infectious organisms, such as bacteria or viruses, to cause diseases. Understanding the biophysics of cell adhesion can help understand these diseases. Discover the latest research on the biophysics of adhesion here.

Adhesion Molecules in Health and Disease

Cell adhesion molecules are a subset of cell adhesion proteins located on the cell surface involved in binding with other cells or with the extracellular matrix in the process called cell adhesion. In essence, cell adhesion molecules help cells stick to each other and to their surroundings. Cell adhesion is a crucial component in maintaining tissue structure and function. Discover the latest research on adhesion molecule and their role in health and disease here.