Ten kilohertz SCS for Treatment of Chronic Upper Extremity Pain (UEP): Results from Prospective Observational Study

Journal of Pain Research
Abram H BurgherJeyakumar Subbaroyan

Abstract

Chronic upper extremity pain (UEP) has complex etiologies and is often disabling. It has been shown that 10 kHz SCS can provide paresthesia-free and durable pain relief in multiple pain types and improve the quality of life of patients. To gain additional evidence on the safety and effectiveness of 10 kHz SCS for the treatment of chronic UEP. It was a prospective, multicenter, and observational study. The study was registered on ClinicalTrials.gov prospectively (clinical trial identifier: NCT02703818). Multicenter. A total of 43 subjects with chronic UEP of ≥5 cm (on a 0-10 cm visual analog scale; VAS) underwent a trial of 10 kHz SCS, and subjects with ≥40% pain relief received a permanent implant. All subjects had upper limb pain at baseline, while some had concomitant shoulder or neck pain. Subject outcomes were assessed for 12 months, and the primary outcome was the responder rate (percentage of subjects experiencing ≥50% pain relief from baseline) at three months. Thirty-eight subjects successfully completed the trial (88.3% success rate), 33 received permanent implants (five withdrew consent), and 32 had device activation (per protocol population). There were no paresthesias or uncomfortable changes in stimulation related ...Continue Reading

References

Dec 1, 1991·American Journal of Epidemiology·M MäkeläA Aromaa
Oct 15, 2003·Arthritis and Rheumatism·Christina GummessonEwald Ornstein
Mar 16, 2007·Expert Review of Medical Devices·Antonio FolettiEric Buchser
Dec 7, 2007·The Journal of Pain : Official Journal of the American Pain Society·Robert H DworkinStojan Zavisic
Oct 1, 2007·Neuromodulation : Journal of the International Neuromodulation Society·Richard B NorthMarc Boulay
Apr 13, 2012·Neuromodulation : Journal of the International Neuromodulation Society·David L PennAshwini D Sharan
Dec 4, 2012·Neuromodulation : Journal of the International Neuromodulation Society·Jean-Pierre Van BuytenThomas Smith
Oct 12, 2013·Neuromodulation : Journal of the International Neuromodulation Society·Timothy R DeerStephanie N Washburn
Dec 7, 2013·Pain Medicine : the Official Journal of the American Academy of Pain Medicine·Adnan Al-KaisyThomas Smith
Sep 27, 2014·Neuromodulation : Journal of the International Neuromodulation Society·Adnan Al-KaisyDavid Pang
Oct 15, 2014·Clinical Neurology and Neurosurgery·Srinivas ChivukulaJohn J Moossy
Mar 5, 2016·Journal of Neurosurgery. Spine·Andrew K ChanLine Jacques
Aug 6, 2016·Neuromodulation : Journal of the International Neuromodulation Society·Sameah HaiderJulie G Pilitsis
Sep 24, 2016·The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques·Adrian B LevineKeith W MacDougall
Oct 28, 2017·Pain Medicine : the Official Journal of the American Academy of Pain Medicine·Adnan Al-KaisyJonathan Lucas
Jun 3, 2018·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Kasra AmirdelfanJeyakumar Subbaroyan
Mar 27, 2019·Annals of Clinical and Translational Neurology·Thomas StaussMohammad Maarouf
Oct 9, 2019·Annals of Clinical and Translational Neurology·Faycal El MajdoubMohammad Maarouf
Dec 18, 2019·Neuromodulation : Journal of the International Neuromodulation Society·Niranjan Khadka, Marom Bikson
Dec 18, 2019·Neuromodulation : Journal of the International Neuromodulation Society·David L Caraway, Kerry Bradley
Jun 7, 2020·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Llknur TelkesJulie G Pilitsis
Jul 2, 2020·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Paul VerrillsDavid Caraway

❮ Previous
Next ❯

Citations

Apr 1, 2021·The Journal of International Medical Research·Kuen Su LeeJae Chul Koh
May 25, 2021·The Journal of International Medical Research·Honghui FengChristopher Bovinet
Jul 13, 2021·Pain Practice : the Official Journal of World Institute of Pain·Vincent GalanDavid Caraway

❮ Previous
Next ❯

Clinical Trials Mentioned

NCT02703818

Software Mentioned

SAS
Excel

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.