Ten-year blood pressure trajectories, cardiovascular mortality, and life years lost in 2 extinction cohorts: the Minnesota Business and Professional Men Study and the Zutphen Study

Journal of the American Heart Association
Susanne M A J TielemansD Kromhout

Abstract

Blood pressure (BP) trajectories derived from measurements repeated over years have low measurement error and may improve cardiovascular disease prediction compared to single, average, and usual BP (single BP adjusted for regression dilution). We characterized 10-year BP trajectories and examined their association with cardiovascular mortality, all-cause mortality, and life years lost. Data from 2 prospective and nearly extinct cohorts of middle-aged men—the Minnesota Business and Professional Men Study (n=261) and the Zutphen Study (n=632)—were used. BP was measured annually during 1947-1957 in Minnesota and 1960-1970 in Zutphen. BP trajectories were identified by latent mixture modeling. Cox proportional hazards and linear regression models examined BP trajectories with cardiovascular mortality, all-cause mortality, and life years lost. Associations were adjusted for age, serum cholesterol, smoking, and diabetes mellitus. Mean initial age was about 50 years in both cohorts. After 10 years of BP measurements, men were followed until death on average 20 years later. All Minnesota men and 98% of Zutphen men died. Four BP trajectories were identified, in which mean systolic BP increased by 5 to 49 mm Hg in Minnesota and 5 to 20 m...Continue Reading

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Citations

Jul 8, 2015·International Journal of Cardiology·Paolo Emilio Puddu, Alessandro Menotti
Aug 25, 2015·International Journal of Cardiology·Alessandro MenottiGiovina Catasta
Jun 12, 2016·International Journal of Cardiology·Paolo Emilio PudduAlessandro Menotti
Jul 18, 2016·Neuromuscular Disorders : NMD·Eugenio MercuriUNKNOWN Trajectory Analysis Project (cTAP)
Aug 23, 2016·International Journal of Cardiology·Alessandro Menotti, Paolo Emilio Puddu
Mar 24, 2017·Journal of Human Hypertension·S M A J TielemansD Kromhout
May 11, 2016·Hypertension·Marileen L P PortegiesM Arfan Ikram
Aug 6, 2018·Journal of Epidemiology and Community Health·Jian-Bing WangKun Chen
Feb 23, 2020·Annals of Medicine·Joel NuotioTeemu Niiranen
Aug 28, 2020·Current Hypertension Reports·Karri SuvilaTeemu J Niiranen
Mar 8, 2019·Journal of Human Hypertension·Denes SteflerMartin Bobak
Nov 18, 2018·Environmental Health : a Global Access Science Source·Samantha Huo Yung KaiYolande Esquirol
May 21, 2021·Journal of the American Heart Association·Barbara N HardingLin Yee Chen
Apr 17, 2021·American Journal of Hypertension·Charles A GermanJoseph Yeboah
Aug 8, 2021·Diabetes Research and Clinical Practice·Cheng-Chieh LinTsai-Chung Li

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