Ten Year Mortality in Different Peripheral Arterial Disease Stages: A Population Based Observational Study on Outcome

European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery
Fredrik SartipyE Wahlberg

Abstract

The aim was to determine long-term mortality rates and the underlying cause of death for subjects with different peripheral arterial disease (PAD) stages in a population based setting. A randomly selected population sample of 5080 subjects was enrolled in the study in 2004-2005. Participants completed health state questionnaires and underwent ankle brachial index (ABI) measurements for classification into PAD severity stages and reference subjects. A follow-up was conducted by the end of 2015 using data from Swedish governmental national registers for cause of death, which was then compared with PAD stage determined at baseline in 2005. The 10 year all cause mortality was 27% for reference cases, 56% for asymptomatic PAD (APAD), 63% for intermittent claudication (IC), and 75% for severe limb ischaemia (SLI). Among all PAD subjects, cardiovascular (CV) causes were the most common main cause of death (45%) and a CV event was present as either the main or one of the three most common contributing causes of death in 64% of the cases. The age adjusted hazard ratios for a main cause of death by a CV event were 1.9 (95% CI 1.5-2.3) for APAD, 2.6 (95% CI 2.1-3.4) for IC, and 3.5 (95% CI 2.3-5.2) for SLI. PAD subjects, including the APA...Continue Reading

Citations

Jul 5, 2019·VASA. Zeitschrift für Gefässkrankheiten·Christian HeissLucia Mazzolai
Jul 16, 2019·European Heart Journal. Quality of Care & Clinical Outcomes·Fredrik SartipyBirgitta Sigvant
Jun 20, 2020·Expert Opinion on Pharmacotherapy·Hani EssaGregory Y H Lip
Sep 16, 2020·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Tanja BöhmeThomas Zeller
Jul 28, 2020·Journal of Endovascular Therapy : an Official Journal of the International Society of Endovascular Specialists·Bhaskar PurushottamPrakash Krishnan
Jan 29, 2021·Arteriosclerosis, Thrombosis, and Vascular Biology·Minghao KouRon C Hoogeveen
Dec 24, 2019·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·Henrik DjerfMårten Falkenberg
Mar 20, 2021·International Angiology : a Journal of the International Union of Angiology·Pavel PoredosArmando Mansilha
Jun 23, 2021·VASA. Zeitschrift für Gefässkrankheiten·Mariya KronlageGrigorios Korosoglou
Oct 15, 2021·European Radiology·Josua A DeckerChristian Scheurig-Muenkler
Nov 9, 2021·VASA. Zeitschrift für Gefässkrankheiten·Jill J F BelchLale Tokgözoğlu
Jan 11, 2022·VASA. Zeitschrift für Gefässkrankheiten·Grigorios Korosoglou, Erwin Blessing

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