Ten-year outcomes of renal tumor radiofrequency ablation

The Journal of Urology
Brett JohnsonJeffrey A Cadeddu

Abstract

We sought to review long-term oncological outcomes of patients with renal tumors treated with radiofrequency ablation (RFA) greater than 10 years ago. Patients with renal tumors that underwent RFA from November 2000 to August 2007 were reviewed retrospectively. Demographic, clinical, and radiologic data were assessed to determine evidence for recurrence of disease. Patients with familial renal cell carcinoma syndromes were excluded from the study. Disease-free survival (DFS), metastasis-free survival (MFS), cancer-specific survival (CSS), and overall survival (OS) were calculated with the Kaplan-Meier method. Subgroup analysis of patients that had at least 10 years follow-up was performed to determine actual 10-year survival. Analysis was also performed based on tumor size. A total of 112 tumors in 106 patients underwent RFA. Median follow-up was 79 months (IQR 28.9 - 121.1) and mean tumor size was 2.5 cm (SD ± 0.8). Initial technical success was achieved in 97% of cases. There were 10 recurrences. Kaplan-Meier six-year disease-free survival and cancer-specific survival was 89% and 96%, respectively. DFS drops to 68% for tumors greater than 3cm. Within the subgroup that had at least 10-year follow-up, actual DFS, CSS, and OS we...Continue Reading

Citations

Jun 10, 2020·Current Oncology Reports·Rand N Wilcox Vanden BergTimothy D McClure
Mar 25, 2020·La Radiologia medica·Massimo De FilippoUmberto Maestroni
Jul 3, 2020·Cardiovascular and Interventional Radiology·Samuel LaRussaTimothy D McClure
Sep 21, 2019·International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group·D FilippiadisF De Cobelli
Feb 18, 2021·Progrès en urologie : journal de l'Association française d'urologie et de la Société française d'urologie·N AmadaneR Boissier

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