Abstract
Nephropathia epidemica (NE) is a hemorrhagic fever with renal syndrome caused by Puumala hantavirus. Its long-term prognosis is considered favorable. There are, however, some reports about subsequent hypertension, glomerular hyperfiltration, and proteinuria after previous hantavirus infection. Therefore, we studied 36 patients 5 and 10 years after acute NE, with 29 seronegative controls. Office blood pressure, ambulatory 24-h blood pressure (ABP), glomerular filtration rate (GFR), and proteinuria were examined. Hypertensive subjects were defined as those patients having increased ambulatory or office blood pressure, or receiving antihypertensive therapy. Office blood pressure was used to define hypertension only if ABP was not determined. At 5 years, the prevalence of hypertension was higher among NE patients than in controls (50 vs 21%, P=0.020). At 10 years, the difference between the groups was no more significant (39 vs 17%, P=0.098). Five years after NE, patients showed higher GFR (121+/-19 vs 109+/-16 ml/min/1.73 m(2), P=0.012) and urinary protein excretion (0.19 g/day, range 0.12-0.38 vs 0.14 g/day, range 0.09-0.24, P=<0.001) than controls. At 10 years, there were no more differences in GFR or protein excretion between t...Continue Reading
References
Oct 1, 1992·Journal of Virology·M N PensieroJ Hay
Jan 1, 1992·Nephron·D Kleinknecht, P E Rollin
Jan 1, 1990·Archives of Virology·R Yanagihara, D J Silverman
Feb 1, 1987·Kidney International·C E Mogensen
Jan 1, 1993·Renal Failure·M ElisafK C Siamopoulos
Jan 1, 1994·Scandinavian Journal of Infectious Diseases·J MustonenA Vaheri
Jan 1, 1994·Archives of Virology·B NiklassonJ LeDuc
Mar 1, 1993·The Journal of Infectious Diseases·G E GlassJ E Childs
Jan 1, 1996·Clinical Immunology and Immunopathology·M TemonenH Holthöfer
May 22, 1996·JAMA : the Journal of the American Medical Association·A W Cowley, R J Roman
Jan 1, 1996·Journal of Clinical Microbiology·O VapalahtiA Vaheri
Jun 1, 1997·Journal of the American Society of Nephrology : JASN·R E SchmiederF C Luft
Mar 6, 1999·Journal of Hypertension
Jul 28, 1999·Clinical and Experimental Hypertension : CHE·J ChalmersT Clark
Nov 27, 1999·Scandinavian Journal of Infectious Diseases·M Brummer-KorvenkontioA Vaheri
May 29, 2000·Scandinavian Journal of Infectious Diseases·B Settergren
Sep 30, 2000·Kidney International·S MäkeläA Pasternack
Jan 29, 2002·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Ilpo Ala-HouhalaAmos Pasternack
Mar 22, 2002·The New England Journal of Medicine·Richard J JohnsonBernardo Rodriguez-Iturbe
Sep 1, 1960·Archives of Internal Medicine·M E RUBINIM E McDOWELL
Oct 3, 2003·The Lancet Infectious Diseases·Olli VapalahtiAntti Vaheri
Dec 4, 2003·The Lancet Infectious Diseases·Jan ClementMarc Van Ranst
Mar 26, 2004·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Hubert WongGuido Filler
Citations
Jun 17, 2011·International Urology and Nephrology·Irinel-Doina MafteiAdrian Covic
May 18, 2010·Nephrology·Denijal TulumovicEnver Zerem
Apr 9, 2010·Clinical Microbiology Reviews·Colleen B JonssonOlli Vapalahti
Jul 22, 2011·Journal of Virology·Ellen KrautkrämerMartin Zeier
Jun 24, 2014·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Christopher BoehlkeElke Neumann-Haefelin
May 5, 2012·Critical Reviews in Microbiology·Maria SargianouGeorge Panos
Jun 8, 2012·Critical Reviews in Microbiology·Marco GoeijenbierEric Van Gorp
May 26, 2006·Kidney International·B Rippe
Nov 16, 2012·Kidney International·Ellen KrautkrämerAlexander Plyusnin
Aug 31, 2013·Kidney International·Joerg LatusNiko Braun
May 9, 2008·Reviews in Medical Virology·Antti VaheriAlexander Plyusnin
Aug 13, 2013·Therapeutic Apheresis and Dialysis : Official Peer-reviewed Journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy·Maja Martinuč BergočJernej Pajek
Jul 5, 2012·Reviews in Medical Virology·Antti VaheriOlli Vapalahti
Oct 14, 2011·Scandinavian Journal of Urology and Nephrology·Robert WagnerKarlheinz Seitz
Jul 21, 2010·Scandinavian Journal of Primary Health Care·Alette BrorstadClas Ahlm
Mar 21, 2015·Human Pathology·Viviane GnemmiDavid Buob
Oct 16, 2013·Antiviral Research·Jukka MustonenAntti Vaheri
Dec 24, 2014·Emerging Infectious Diseases·Joerg LatusNiko Braun
Oct 16, 2016·BMC Infectious Diseases·Kristina Bergstedt OscarssonClas Ahlm
Jan 5, 2017·Infectious Diseases·Jukka MustonenSatu Mäkelä
May 19, 2018·Emerging Infectious Diseases·Maxime HentzienAmélie Servettaz
Mar 4, 2009·Expert Review of Anti-infective Therapy·Paul HeymanTatjana Avsic-Zupanc
Dec 22, 2010·Expert Review of Anti-infective Therapy·Jonas Klingström, Clas Ahlm
Jul 19, 2018·Disease Markers·Xiude FanZhengwen Liu
Jul 25, 2019·Viruses·Silja NiskanenTarja Sironen
Jun 1, 2008·NDT Plus·Katharina FriebeMarkus Krautter
May 14, 2019·Infectious Diseases·Maria FurbergBarbara Schumann
Aug 1, 2020·Pathogens·Paula MantulaTuula Outinen
Aug 22, 2013·Deutsches Ärzteblatt International·Detlev H KrügerJörg Hofmann
Mar 21, 2017·Kidney International·Eric SiddallJai Radhakrishnan
Aug 5, 2021·Experimental and Therapeutic Medicine·Gabriela LupuşoruGener Ismail
Aug 29, 2021·Viruses·Antti VaheriJukka Mustonen