Ten-year study of postoperative complications following dental extractions in patients with inherited bleeding disorders

International Journal of Oral and Maxillofacial Surgery
J-T HsiehM Batstone

Abstract

Dental extractions challenge the body's haemostatic mechanism. Postoperative bleeding from dental extraction can be prolonged, or even life threatening in patients with inherited bleeding disorders. Pre- and postoperative clotting factor replacements or systemic desmopressin (ddAVP) have been advocated at our institution to prevent bleeding complications in these patients. This study aimed to assess the postoperative bleeding rate in patients with inherited bleeding disorders that underwent dental extractions at our institution between 2003 and 2012. Patients with inherited bleeding disorders such as haemophilia A, haemophilia B, and von Willebrand's disease were included. Retrospective chart review was conducted. The result showed 53 extraction events occurred in 45 patients over the 10-year period. Ten out of 53 extraction events (18.9%) had postoperative bleeding requiring further factor replacement or ddAVP. Postoperative bleeding in one patient with mild haemophilia A was complicated by the development of inhibitors. Type and severity of bleeding disorder, bone removal, and use of a local haemostatic agent did not have any significant effect on postoperative bleeding. Despite the use of perioperative factors and desmopress...Continue Reading

Citations

Jan 22, 2020·Haemophilia : the Official Journal of the World Federation of Hemophilia·Branislav Bajkin, Alison Dougall
Mar 10, 2021·The British Journal of Oral & Maxillofacial Surgery·Takahiro YagyuuTadaaki Kirita
Sep 28, 2020·International Journal of Surgery Case Reports·Ambre BellotBérengère Phulpin

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