Ten years after the Dutch public health campaign on folic acid: the continuing challenge.

European Journal of Clinical Pharmacology
H E K de Walle, L T W de Jong-van den Berg

Abstract

Folic acid use in the periconceptional period reduces the risk of neural tube defects (NTDs). However, applying this knowledge in daily practice is not an easy task. We report here the current level of folic acid use in the Netherlands and discuss the figures within the framework of a national governmental campaign held in 1995 promoting the use of folic acid and the professional interventions undertaken since then. We carried out six studies in the northern Netherlands during 1995, 1996, 1998, 2000, 2003 and 2005, respectively. The same methodology in the same health professionals' practices was followed in all studies. Pregnant women attending their first or second antenatal visit were asked to fill in a questionnaire aimed at assessing their awareness and use of folic acid. In 2005, most of the pregnant women used folic acid "at some time in their pregnancy", and 51% used it for the entire advised period. Prior knowledge on the protective affect of folic acid and on the period of use was strongly related to the level of education. The use of folic acid in a previous pregnancy [odds ratio (OR) 3.9, 95% confidence interval (95% CI) 1.6-9.9], the use of an oral contraceptive (OR 2.1, 95% CI 1.1-4.1) and parity (OR 0.08, 95% CI ...Continue Reading

References

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Citations

Jul 15, 2011·Human Reproduction·Fatima HammicheRégine P M Steegers-Theunissen
Jul 12, 2011·The Cleft Palate-craniofacial Journal : Official Publication of the American Cleft Palate-Craniofacial Association·Alice C MichelsRene R Van der Hulst
May 14, 2011·American Journal of Public Health·Nureen Sumar, Lindsay McLaren
Apr 22, 2014·Reproductive Biomedicine Online·T MurtoA Stavreus-Evers
Oct 11, 2013·Public Health Nutrition·Judith ManniënEileen K Hutton
Nov 28, 2012·Women's Health·Anita L Nelson
Nov 25, 2014·Italian Journal of Pediatrics·Pierpaolo MastroiacovoGioacchino Scarano
Apr 3, 2009·Paediatric and Perinatal Epidemiology·Ester Garne, Hermien de Walle
Jun 3, 2009·BJOG : an International Journal of Obstetrics and Gynaecology·M LoaneUNKNOWN EUROCAT Working Group
Jan 17, 2012·Birth Defects Research. Part A, Clinical and Molecular Teratology·Priscilla A Zetstra-van der WoudeLolkje T W de Jong-van den Berg
Feb 11, 2011·Acta Obstetricia Et Gynecologica Scandinavica·Tanja TydénClara Aarts
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May 22, 2019·Nutrients·Aurore CamierBlandine de Lauzon-Guillain
May 11, 2011·Deutsches Ärzteblatt International·Wolfgang Herrmann, Rima Obeid
Nov 13, 2020·Birth Defects Research·Romy van de PutteIris A L M van Rooij

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