Ten years of experience with MRI follow-up of testicular cancer stage I: a retrospective study and an MRI protocol with DWI.

Acta Oncologica
Solveig Kärk Abildtrup LarsenErik Morre Pedersen

Abstract

Patients with testicular cancer (TC) are mainly young and survival rates are high. MRI has several times been proposed to replace CT in follow-up of this patient group to reduce image-related radiation exposure. However, current evidence is scarce for the use of MRI in this context. First, to retrospectively evaluate the ability of MRI of the retroperitoneum and pelvis to detect relapse in patients with TC stage I. Second, to present a relevant MRI protocol of the retroperitoneum and pelvis with diffusion weighted imaging (DWI). A retrospective analysis of written radiology reports compared to clinical data from clinical practice from 2010 to 2018. The cohort consists of 2487 MRIs of the retroperitoneum and pelvis in 759 patients with TC stage I (524 seminoma (69.0%), 235 non-seminoma (31.0%)), including 102 patients (13.4%) with confirmed relapse. Confirmed relapse was defined when treatment was initiated for metastatic TC. Ninety-five patients had a relapse in the MRI scan field during follow-up. MRI of the retroperitoneum and pelvis showed a high sensitivity of 93.8% and a high specificity of 97.4% for detecting TC relapse. The sensitivity for detecting relapse ≥10 mm in short axis lymph node diameter was 100%. The negative ...Continue Reading

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Citations

Aug 31, 2021·European Journal of Radiology Open·Andrés Felipe Herrera OrtizFreddy Fernando Fonseca López
Nov 16, 2021·World Journal of Urology·Gamal Anton WakilehFriedemann Zengerling

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