PMID: 15348335Sep 7, 2004Paper

Tensile properties of a bone cement containing non-ionic contrast media

Journal of Materials Science. Materials in Medicine
F KjellsonL Lidgren

Abstract

The addition of contrast media such as BaSO4 or ZrO2 to bone cement has adverse effects in joint replacements, including third body wear and particle-induced bone resorption. Ground PMMA containing particles of the non-ionic water-soluble iodine-based X-ray contrast media, iohexol (IHX) and iodixanol (IDX), has, in bone tissue culture, shown less bone resorption than commercial cements. These water-soluble non-ceramic contrast media may change the mechanical properties of acrylic bone cement. The static mechanical properties of bone cement containing either IHX or IDX have been investigated. There was no significant difference in ultimate stress between Palacos R (with 15.0 wt % of ZrO2) and plain cement with 8.0 wt % of IHX or IDX with mass median diameter (MMD) of 15.0 or 16.0 microm, while strain to failure was higher for the latter (p < 0.02). The larger particles (15.0 or 16.0 microm) gave significantly higher (p < 0.001) ultimate tensile strengths and strains to failure than smaller sizes (2.4 or 3.6 microm). Decreasing the amount of IHX from 10.0 wt % to 6.0 wt % gave a higher ultimate tensile strength (p < 0.001) and strain to failure (p < 0.02). Scanning electron microscopy (SEM) showed the smaller contrast media parti...Continue Reading

Citations

Sep 24, 2004·Journal of Biomedical Materials Research. Part a·F KjellsonL Lidgren
Jul 20, 2006·Journal of the Royal Society, Interface·J S WangL Lidgren
Dec 11, 2002·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·A ArtolaM Gurruchaga
Feb 1, 2007·Journal of Materials Science. Materials in Medicine·Fred KjellsonLars Lidgren
Jun 26, 2007·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Gladius Lewis
Apr 9, 2004·Journal of Biomaterials Applications·J M ManeroM Gurruchaga
Jul 21, 2004·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·F KjellsonL Lidgren

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