Tension/stiffness ratio of skinned rat skeletal muscle fibre types at various temperatures

Acta Physiologica Scandinavica
S Galler, K Hilber

Abstract

It is well known that shortening velocity and maximal tension of muscle preparations are strongly dependent on experimental temperature. Conversely, studies about temperature effects on muscle fibre stiffness are scarce. In the present study, we measured tension and stiffness of maximally Ca2+-activated skinned rat skeletal muscle fibres of different types over a wide temperature range. All fibre types exhibited a similar tension/stiffness ratio at each experimental temperature. This ratio increased almost linearly from 6 to 18 nm when the temperature was raised from 6 to 34 degrees C. Our results are discussed in the light of the drastic discrepancies reported for the amount of compliance inside and outside the attached myosin cross-bridges of activated muscle fibres (Ford et al. 1981, Huxley et al. 1994, Kojima et al. 1994, Wakabayashi et al. 1994, Higuchi et al. 1995). The relation between these compliances had been deduced from various experimental approaches executed at different temperatures. The large temperature sensitivity of the tension/stiffness ratio found in this study provides evidence for the assumption that the compliance outside the cross-bridges increases with rising temperature. This view would reconcile the ...Continue Reading

References

May 1, 1992·The Journal of General Physiology·D A Martyn, A M Gordon
Dec 1, 1991·Proceedings of the National Academy of Sciences of the United States of America·B Brenner
Jun 1, 1988·Biophysical Journal·P B Chase, M J Kushmerick
Nov 1, 1987·The Journal of Physiology·Y E GoldmanK W Ranatunga
Oct 22, 1971·Nature·A F Huxley, R M Simmons
Feb 1, 1981·The Journal of Physiology·L E FordR M Simmons
Dec 20, 1994·Proceedings of the National Academy of Sciences of the United States of America·H KojimaT Yanagida
Sep 1, 1995·Biophysical Journal·H HiguchiY E Goldman
Apr 1, 1996·Physiological Reviews·S Schiaffino, C Reggiani
May 15, 1996·The Journal of Physiology·S GallerD Pette
Aug 1, 1996·Journal of Muscle Research and Cell Motility·A F Huxley, S Tideswell

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Citations

Oct 3, 2007·European Journal of Applied Physiology·William P S McKayBrian L F Daku
Oct 3, 2009·Pflügers Archiv : European journal of physiology·Julien OchalaLars Larsson
Mar 28, 2009·Proceedings of the National Academy of Sciences of the United States of America·Julien S Davis, Neal D Epstein
Apr 25, 2007·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Julien OchalaLisa S Krivickas
Sep 9, 2011·Proceedings. Biological Sciences·Kiisa C NishikawaStan L Lindstedt
Sep 29, 2012·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Nima AlamdariPer-Olof Hasselgren
Aug 4, 2010·The Journal of Physiology·C J BarclayN A Curtin
Feb 27, 2010·Journal of Electromyography and Kinesiology : Official Journal of the International Society of Electrophysiological Kinesiology·H Drzymała-CelichowskaJ Celichowski
Jan 30, 2007·Biophysical Journal·Julien S Davis, Neal D Epstein
Jun 28, 2003·Biophysical Journal·Julien S Davis, Neal D Epstein
Dec 7, 2010·Journal of Muscle Research and Cell Motility·Gerald Offer, K W Ranatunga
Mar 5, 2004·American Journal of Physiology. Cell Physiology·T Radzyukevich, K A P Edman
Oct 5, 2019·International Journal of Molecular Sciences·Carlo Knupp, John M Squire
Sep 5, 2014·American Journal of Physiology. Cell Physiology·Cassandra R NelsonRobert H Fitts
Aug 20, 2021·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Henning T LangerKeith Baar

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