Terahertz optical measurements of correlated motions with possible allosteric function

Biophysics Reviews
Katherine A NiessenA G Markelz

Abstract

A suggested mechanism for allosteric response is the distortion of the energy landscape with agonist binding changing the protein structure's access to functional configurations. Intramolecular vibrations are indicative of the energy landscape and may have trajectories that enable functional conformational change. Here, we discuss the development of an optical method to measure the intramolecular vibrations in proteins, namely, crystal anisotropy terahertz microscopy, and the various approaches which can be used to identify the spectral data with specific structural motions.

References

Aug 1, 1990·Journal of Biomolecular Structure & Dynamics·T WeidlichG A Thomas
Jun 1, 1988·Biopolymers·S M LindsayA Rupprecht
Sep 1, 1986·Biopolymers·R E BruccoleriJ A McCammon
Feb 1, 1997·Journal of Biomolecular Structure & Dynamics·V LisyL Chinsky
Jun 1, 1997·Protein Science : a Publication of the Protein Society·E W ChungC V Robinson
May 1, 1987·Physical Review A: General Physics·J W PowellW Peticolas
Jun 13, 2002·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·D L WoolardW R Loerop
Jun 13, 2002·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·K AchterholdF G Parak
May 1, 1965·Journal of Molecular Biology·J MONODJ P CHANGEUX
Aug 13, 2004·Philosophical Transactions. Series A, Mathematical, Physical, and Engineering Sciences·Thomas W CroweJeffrey L Hesler
Aug 25, 2004·Physical Review Letters·Erika BalogJeremy C Smith
Sep 24, 2004·Proteins·K GunasekaranRuth Nussinov
May 5, 2005·Proceedings of the National Academy of Sciences of the United States of America·M Karplus, J Kuriyan
Jun 4, 2005·Science·Jean-Pierre Changeux, Stuart J Edelstein
Sep 7, 2005·Current Opinion in Structural Biology·Ivet Bahar, A J Rader
Dec 20, 2005·Biophysical Journal·Paula Petrone, Vijay S Pande
Aug 20, 2008·Optics Express·Reshmi ChakkittakandyPaul C Planken
Oct 15, 2008·Physical Review Letters·Ralf BiehlDieter Richter
Oct 2, 2009·Physical Review Letters·Maikel C RheinstädterDieter Strauch
Feb 16, 2011·Biophysical Journal·Yunfen HeA G Markelz
May 11, 2011·The Journal of Physical Chemistry. B·Erika BalogFranci Merzel
Sep 20, 2011·Nature Structural & Molecular Biology·Moran GrossmanMartina Havenith
Mar 6, 2012·Proceedings of the National Academy of Sciences of the United States of America·Hesam N Motlagh, Vincent J Hilser
May 15, 2012·Annual Review of Biophysics·Vincent J HilserHesam N Motlagh
Oct 9, 2012·The Journal of Physical Chemistry. a·Rohit SinghAndrea G Markelz
Apr 16, 2013·Cell·Ruth Nussinov, Chung-Jung Tsai
Jun 14, 2013·Biochemistry·David D BoehrPeter E Wright
Sep 26, 2013·Methods in Molecular Biology·Vincent J Hilser, Steven T Whitten
Oct 1, 2013·Nature Structural & Molecular Biology·Gira BhabhaPeter E Wright
Jan 17, 2014·Nature Communications·Gheorghe AcbasA G Markelz
Jun 4, 2014·Nature Communications·David A TurtonKlaas Wynne

❮ Previous
Next ❯

Citations

Feb 7, 2017·Physical Chemistry Chemical Physics : PCCP·Anna Kuffel
Nov 10, 2015·The Journal of Chemical Physics·Yao Xu, Martina Havenith
Nov 7, 2019·Optics Express·Katherine NiessenA G Markelz
Nov 29, 2020·Genes to Cells : Devoted to Molecular & Cellular Mechanisms·Masahiko ImashimizuHiromichi Hoshina
Mar 16, 2017·Biophysical Journal·Katherine A NiessenAndrea G Markelz
Jul 3, 2021·Biophysical Journal·Luis Alberto Esteves Batista de CarvalhoMaria Paula Matos Marques
Oct 11, 2017·The Journal of Physical Chemistry. B·Valeria Conti NibaliGiorgio Colombo

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

© 2022 Meta ULC. All rights reserved