PMID: 6406515Jun 1, 1983Paper

Teratocarcinoma stem cell adhesion: the role of divalent cations and a cell surface lectin

The Journal of Cell Biology
L B GrabelS D Rosen

Abstract

We describe two additive systems of intercellular adhesion in teratocarcinoma stem cells (Nulli cell line). One component is divalent cation-dependent (Ca++ or Mg++) and the other involves a cell surface fucan/mannan-specific lectin, previously identified on stem cells by an erythrocyte rosetting assay. The existence of these two systems is inferred from the observation that reaggregation of stem cells was partially inhibited by the removal of divalent cations or by the presence of lectin inhibitors such as fucoidan, but reaggregation was completely blocked when the two conditions were combined. Our results are related to recent work describing a calcium-dependent system of intercellular adhesion in teratocarcinoma stem cells.

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Citations

Jan 1, 1987·Cancer Investigation·H J Gabius
Mar 1, 1986·Experimental Cell Research·B Obrink
Jan 1, 1989·Developmental Genetics·J W Littlefield
Dec 1, 1987·The Journal of Experimental Zoology·S J KimberP R Bagley
Dec 4, 1984·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·E F Wagner
Feb 19, 1985·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·T M Jessell, J Dodd
May 1, 1990·Roux's Archives of Developmental Biology : the Official Organ of the EDBO·Esmond J SandersIrene M Ledsham
Jan 1, 1987·Roux's Archives of Developmental Biology : the Official Organ of the EDBO·Gillian Barbara Dealtry, Martin Howard Sellens
Jan 1, 1984·Biochimica Et Biophysica Acta·E Roos
Jan 1, 1985·Biochimica Et Biophysica Acta·J M Vasiliev

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