Teratocarcinosarcoma of the oral cavity

Pediatric Blood & Cancer
Roman CrazzolaraAndreas Klein-Franke

Abstract

Teratocarcinosarcoma (TCS) is a very rare and aggressive neoplasm characterized by teratoma and carcinosarcoma components. The authors report on a case of TCS in the oral cavity of a child. Rapid growth and extensive local destruction were prominent features prior to treatment. Histologic examination revealed various tissue elements, such as epithelial, mesenchymal, and neuroectodermal components. Chemotherapy was effective in reducing tumor mass, followed by partial anterior mandibulectomy and reconstruction with composite microvascular tissue transfer. The approach allowed radical resection of the tumor and functional reconstruction with excellent aesthetic results.

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Citations

Mar 1, 2009·Head and Neck Pathology·Shubhada V KanePrathmesh S Pai
Sep 1, 2012·Journal of Pediatric Hematology/oncology·Neeraj AgrawalArnold C Paulino
Aug 2, 2008·Journal of Neurosurgery·C C Tchoyoson LimIvan Ng
Jun 5, 2013·American Journal of Otolaryngology·Poonam MisraJean Anderson Eloy
Mar 7, 2013·Annals of Diagnostic Pathology·Syeda Samia FatimaZubair Ahmad
Nov 11, 2008·Annals of Diagnostic Pathology·Shi WeiNasser Said-Al-Naief
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Jun 20, 2007·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·Yi-Shing Lisa ChengYuk-Kwan Chen
May 20, 2016·Journal of Oral and Maxillofacial Pathology : JOMFP·Soham ChakrabortyGoutam Bandyopadhyay
Aug 28, 2012·International Journal of Surgical Pathology·Shudong YangJun Rui
Jan 5, 2013·Ear, Nose, & Throat Journal·Shafik N WassefLarry L Myers

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