Oct 8, 1989

Terminal arbors of single ON-center and OFF-center X and Y retinal ganglion cell axons within the ferret's lateral geniculate nucleus

The Journal of Comparative Neurology
A W RoeM Sur


The lateral geniculate nucleus of the ferret contains not only eye-specific layers, but a further subdivision of layers A and A1 into inner and outer sublaminae that contain, respectively, ON-center and OFF-center cells (Stryker and Zahs, '83). To study how the arbors of single retinal ganglion cell axons correlate with these cellular divisions, we have examined the morphology of physiologically classified retinal axons in the ferret's lateral geniculate nucleus. As in cats, we could classify retinal axons as X or Y on the basis of a number of physiological criteria. X and Y axons have distinct patterns of termination in the lateral geniculate nucleus. Contralateral X axons innervate lamina A and ipsilateral axons lamina A1. X axons are further segregated in these laminae so that ON-center axons terminate in the inner sublamina, and OFF-center axons in the outer sublamina. We did not observe any branches of X axons innervating the medial interlaminar nucleus or the midbrain. Y axons have much larger terminal arbors and exhibit greater variation in their terminations. Generally, within layers A and A1, ON-center Y axons innervate the inner sublamina and OFF-center Y axons innervate the outer sublamina. However, they often innerv...Continue Reading

  • References19
  • Citations10


Mentioned in this Paper

Biochemical Pathway
Entire Lateral Geniculate Body
Axonal Transport
Blade - plant part
Dorsal Nucleus of Lateral Geniculate Body
Science of Morphology
Entire Midbrain
Lamiinae (invertebrate)
Cell Nucleus

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