Termination of pregnancy among very preterm births and its impact on very preterm mortality: results from ten European population-based cohorts in the MOSAIC study

BJOG : an International Journal of Obstetrics and Gynaecology
E PapiernikMOSAIC Research group

Abstract

To study the impact of terminations of pregnancy (TOP) on very preterm mortality in Europe. European prospective population-based cohort study. Ten regions from nine European countries participating in the MOSAIC (Models of OrganiSing Access to Intensive Care for very preterm babies) study. These regions had different policies on screening for congenital anomalies (CAs) and on pregnancy termination. Births 22-31 weeks gestational age. The analysis compares the proportion of TOP among very preterm births and assesses differences in mortality between the regions. Pregnancy outcomes (termination, antepartum death, intrapartum death and live birth) and reasons for termination, presence of CAs and causes of death for stillbirths and live births in 2003. Pregnancy terminations constituted between 1 and 21.5% of all very preterm births and between 4 and 53% of stillbirths. Most terminations were for CAs, although some were for obstetric indications (severe pre-eclampsia, growth restriction, premature rupture of membranes). TOP contributed substantially to overall fetal mortality rates in the two regions with late second-trimester screening. There was no clear association between policies governing screening and pregnancy termination a...Continue Reading

References

Oct 1, 1994·Paediatric and Perinatal Epidemiology·M GisslerE Hemminki
Nov 27, 1999·Obstetrics and Gynecology·O M Faye-PetersenK D Wenstrom
Apr 18, 2000·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Y LinhartM Mazor
Nov 4, 2000·The Journal of Pediatrics·R De LeeuwUNKNOWN EURONIC study group
Mar 26, 2002·JAMA : the Journal of the American Medical Association·Shiliang LiuUNKNOWN Fetal and Infant Health Study Group of the Canadian Perinatal Surveillance System
Dec 4, 2003·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Simone BuitendijkJean Bottu
Apr 24, 2004·BJOG : an International Journal of Obstetrics and Gynaecology·Babak KhoshnoodFrançois Goffinet
Dec 25, 2004·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·E GarneI Barisic
Jun 30, 2005·Biology of the Neonate·Marcello Orzalesi, Marina Cuttini
Nov 1, 2005·Seminars in Neonatology : SN·Jennifer ZeitlinUNKNOWN EUROPET Group

❮ Previous
Next ❯

Citations

Jul 28, 2010·Clinical Obstetrics and Gynecology·Ruth Fretts
Nov 24, 2011·PloS One·Ashna D MohangooUNKNOWN Euro-Peristat Scientific Committee
Dec 3, 2013·Seminars in Fetal & Neonatal Medicine·Lucy K SmithDavid Field
May 1, 2008·Journal of Perinatology : Official Journal of the California Perinatal Association·J Gadzinowski
Oct 15, 2013·Journal de gynécologie, obstétrique et biologie de la reproduction·B Blondel, J Zeitlin
Jan 8, 2013·Journal de gynécologie, obstétrique et biologie de la reproduction·J Fresson, B Blondel
Mar 20, 2012·Archives de pédiatrie : organe officiel de la Sociéte française de pédiatrie·G BoussicaultJ-C Rozé
Jan 20, 2010·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Jennifer ZeitlinUNKNOWN MOSAIC Research group
Jul 28, 2011·BJOG : an International Journal of Obstetrics and Gynaecology·K HemmingJ L Hutton
Apr 9, 2010·BJOG : an International Journal of Obstetrics and Gynaecology·E GarneUNKNOWN EUROCAT Working Group
Sep 6, 2015·BMC Pediatrics·Paromita Deb-RinkerUNKNOWN Canadian Perinatal Surveillance System Public Health Agency of Canada
Jan 7, 2015·Obstetrics and Gynecology·Jennifer A HutcheonHyagriv N Simhan
Jan 1, 2016·Journal of Epidemiology and Community Health·Jennifer ZeitlinUNKNOWN Euro-Peristat Scientific Committee
Oct 21, 2016·BJOG : an International Journal of Obstetrics and Gynaecology·M DelnordUNKNOWN Euro-Peristat Scientific Committee
Feb 7, 2009·Journal of Perinatal Medicine·Anteo Di NapoliMarcello Orzalesi
Nov 17, 2009·Journal of Perinatal Medicine·Birgit Arabin
Aug 3, 2020·Acta Obstetricia Et Gynecologica Scandinavica·Ellen RoetsKim Beernaert
Aug 8, 2015·Cadernos de saúde pública·Antônio Augusto Moura da SilvaMarco Antonio Barbieri
Aug 5, 2018·BMC Pediatrics·Laure DombrechtUNKNOWN NICU consortium
Feb 8, 2020·International Journal of Epidemiology·Jennifer ZeitlinUNKNOWN EPICE and SHIPS Research Group
Sep 3, 2010·Journal of Perinatal Medicine·Daniel W SkupskiManuel Carrapato
Jan 22, 2018·Archives of Disease in Childhood. Fetal and Neonatal Edition·Anna Karin Edstedt BonamyUNKNOWN Epice Research Group

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.