PMID: 25726780Jan 1, 2014Paper

Test scores as indicators of treatment efficacy in dementia caused by Alzheimer's disease in clinical practice

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova
S I Gavrilova, I V Kolykhalov

Abstract

To analyze the possibility of using MMSE and CGIS as well as the Clock drawing test for the objectification of treatment efficacy in Alzheimer's disease (AD). Authors examined 765 patients with mild and moderate dementia treated with donepezil during 3 months. The efficacy was assessed using the MMSE and CGIS. The methods demonstrated the reproducibility compared to those used in earlier clinical trials and efficacy of donepezile in the treatment of mild and moderate AD, the Clock drawing test can be recommended as an additional technique for assessment of treatment efficacy in relation to opticospatial function.

References

May 15, 1999·Dementia and Geriatric Cognitive Disorders·A BurnsL T Friedhoff
May 5, 2000·The Cochrane Database of Systematic Reviews·S Birks J, D Melzer
Aug 15, 2001·Neurology·B WinbladUNKNOWN Donepezil Nordic Study Group
Oct 25, 2002·Journal of Neurology, Neurosurgery, and Psychiatry·K RockwoodUNKNOWN ACADIE Investigators
Aug 15, 2003·The Cochrane Database of Systematic Reviews·J S Birks, R Harvey
Sep 18, 2004·Archives of Gerontology and Geriatrics·Y BarakD Aizenberg
Jul 17, 2009·Psychogeriatrics : the Official Journal of the Japanese Psychogeriatric Society·Motohiro NozawaHeii Arai
Oct 2, 2009·Journal of the American Geriatrics Society·Rohini K HernandezElizabeth V Lawler

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Citations

Apr 17, 2015·BMC Neurology·Raed Abdullah AlroughaniJasem Yousef Al-Hashel

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