Testicular and spermatotoxic potential of methanol extract of red cultivar Allium cepa in rats.

Journal of Complementary & Integrative Medicine
Oyewusi J AdeoyeAdebiyi A Adekunle

Abstract

Background In both human and animals, especially in food and companion animal breeding farms, infertility is normally a challenge of great concern. Males have been found to be solely responsible for about 20-30% of infertility cases. Allium cepa (Onion), being one of the highly consumed spices worldwide, is usually overlooked as a possible reproductive toxicant. Most research on A. cepa document its medicinal effects. This study focused on toxicity potential of A. cepa to the male reproductive system. Spermatozoa morphological characteristics and testicular histopathology of male Wistar rats were accessed following administration of A. cepa methanol extract for 14 and 28 days. Methods The rats (55) were divided into groups A, B and C of 25, 25 and 5 rats, respectively. Group C served as the control and was administered distilled water (10 ml/kg), while groups A and B were subdivided into five groups of five rats each. Group A and B were administered A. cepa extract at various graded doses for 14 days and 28 days, respectively. Results The results revealed significantly increased (p < 0.05) percentage spermatozoa abnormalities, with significantly lower spermatozoa concentration, mass activity and percentage sperm motility when c...Continue Reading

References

Feb 1, 1970·Journal of Dairy Science·M E Wells, O A Awa
Jul 1, 1997·Journal of Assisted Reproduction and Genetics·A BenshushanA Lewin
Mar 20, 2001·British Medical Bulletin·R M Sharpe
May 15, 2010·Journal of Andrology·F HammicheR P M Steegers-Theunissen
Jan 1, 2009·African Journal of Traditional, Complementary, and Alternative Medicines : AJTCAM·Omonike O Ogbole, Edith O Ajaiyeoba
Aug 8, 2012·Journal of Human Reproductive Sciences·Serah F IgeUtibe-Abasi S Udoh
Nov 20, 2012·Journal of Human Reproductive Sciences·Serah F Ige, Roland E Akhigbe
Apr 11, 2013·Journal of Food Science and Technology·Lipi DasRunu Chakraborty
Apr 29, 2014·Expert Opinion on Drug Safety·Jessica L Verpeut, Nicholas T Bello
Jul 2, 2014·Evidence-based Complementary and Alternative Medicine : ECAM·Ng Cho PingDurriyyah Sharifah Hasan Adli
May 1, 2015·Reproductive Biology and Endocrinology : RB&E·Ashok AgarwalMichelle Renee Chyatte

❮ Previous
Next ❯

Citations


❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.