Testing for genetic evidence of population expansion and contraction: an empirical analysis of microsatellite DNA variation using a hierarchical Bayesian model

Evolution; International Journal of Organic Evolution
Jay F Storz, Mark A Beaumont

Abstract

The role of past climatic change in shaping the distributions of tropical rain forest vertebrates is central to long-standing hypotheses about the legacy of the Quaternary ice ages. One approach to testing such hypotheses is to use genetic data to infer the demographic history of codistributed species. Population genetic theory that relates the structure of allelic genealogies to historical changes in effective population size can be used to detect a past history of demographic expansion or contraction. The fruit bats Cynopterus sphinx and C. brachyotis (Chiroptera: Pteropodidae) exhibit markedly different distribution patterns across the Indomalayan region and therefore represent an exemplary species pair to use for such tests. The purpose of this study was to test alternative hypotheses about historical patterns of demographic expansion and contraction in C. sphinx and C. brachyotis using a coalescent-based analysis of microsatellite variation. Specifically, we used a hierarchical Bayesian model based on Markov chain Monte Carlo simulations to estimate the posterior distribution of genealogical and demographic parameters. The results revealed strong evidence for population contraction in both species. Evidence for a populatio...Continue Reading

References

Nov 1, 1988·Genetics·R R Hudson, N L Kaplan
Jul 18, 1995·Proceedings of the National Academy of Sciences of the United States of America·D B GoldsteinM W Feldman
Apr 12, 1994·Proceedings of the National Academy of Sciences of the United States of America·A Di RienzoN B Freimer
Aug 1, 1993·Genetics·B CharlesworthD Charlesworth
Dec 1, 1995·Genetics·R R Hudson, N L Kaplan
Jan 1, 1995·Annual Review of Genetics·P Donnelly, S Tavaré
Dec 1, 1996·Genetics·J GoudetF Rousset
Feb 1, 1997·Genetics·S TavaréP Donnelly
May 1, 1997·Genetics·M C Whitlock, N H Barton
Apr 1, 1997·Genitourinary Medicine·J D AminA M Mai
Mar 21, 1998·Proceedings of the National Academy of Sciences of the United States of America·H C HarpendingS T Sherry
Jun 19, 1998·American Journal of Human Genetics·B BrinkmannB Rolf
Jul 8, 1998·Proceedings of the National Academy of Sciences of the United States of America·D E Reich, D B Goldstein
Sep 2, 1998·Genetics·I J Wilson, D J Balding
Dec 3, 1999·Genetics·J Wakeley
Dec 22, 1999·Molecular Biology and Evolution·J K PritchardM W Feldman
Mar 18, 2000·Science·K J Willis, R J Whittaker
Apr 4, 2000·Genetics·R GonserA Di Rienzo
Jun 22, 2000·Proceedings of the National Academy of Sciences of the United States of America·R ThomsonM W Feldman
Nov 10, 2000·Chromosoma·C Schlötterer
Dec 9, 2000·Molecular Biology and Evolution·J P KingR Chakraborty

❮ Previous
Next ❯

Citations

May 17, 2006·Trends in Ecology & Evolution·Mark A Beaumont
Nov 16, 2011·Proceedings of the National Academy of Sciences of the United States of America·Virginie HutsemékersAlain Vanderpoorten
Sep 6, 2012·Proceedings of the National Academy of Sciences of the United States of America·Michaël C FontaineFréderic Austerlitz
Apr 26, 2003·Proceedings. Biological Sciences·Thierry Wirth, Louis Bernatchez
Apr 23, 2010·Conservation Biology : the Journal of the Society for Conservation Biology·Lifeng ZhuFuwen Wei
Dec 15, 2010·BMC Evolutionary Biology·Rosa AgudoJosé Antonio Donázar
Aug 15, 2009·PLoS Genetics·Samrat MondolUma Ramakrishnan
Sep 20, 2008·PLoS Pathogens·Thierry WirthStefan Niemann
Sep 14, 2004·PLoS Biology·Elizabeth A HadlyChris J Conroy
Jan 19, 2006·PLoS Biology·Benoît GoossensMichael W Bruford
Feb 20, 2016·BMC Evolutionary Biology·Balaji ChattopadhyayUma Ramakrishnan
Sep 16, 2015·Conservation Biology : the Journal of the Society for Conservation Biology·Zhijin LiuMing Li
Nov 3, 2009·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·J S Lopes, M A Beaumont
Sep 26, 2013·Evolutionary Applications·Trishna DuttaJohn Seidensticker

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.