PMID: 15228167Jul 2, 2004Paper

Testing for the undetectable in drug-facilitated sexual assault using hair analyzed by tandem mass spectrometry as evidence

Therapeutic Drug Monitoring
P KintzBertrand Ludes

Abstract

The use of a drug to modify a person's behavior for criminal gain is not a recent phenomenon. However, the recent increase in reports of drug-facilitated crimes (sexual assault, robbery) has caused alarm in the general public. Drugs involved can be pharmaceuticals such as benzodiazepines (flunitrazepam, lorazepam, etc), hypnotics (zopiclone, zolpidem), sedatives (neuroleptics, some histamine H, antagonists), or anesthetics (gamma-hydroxybutyrate, ketamine), drugs of abuse such as cannabis, ecstasy, or lysergide, or more often ethanol. Drugs used to facilitate sexual assaults can be difficult to detect (active products at low dosages, chemical instability), possess amnesic properties, and can be rapidly cleared from the body (short half-life). In these situations, blood or even urine can be of little interest. This is the reason why this laboratory developed an original approach based on hair testing. Hair was suggested as a valuable specimen in situations where, as a result of a delay in reporting the crime, natural processes have eliminated the drug from typical biologic specimens. Although there are many papers focused on the identification of drugs in hair following chronic drug use, those dealing with a single dose are very...Continue Reading

References

Jan 1, 1996·European Journal of Clinical Pharmacology·D E RollinsG G Krueger
Aug 23, 2001·Science & Justice : Journal of the Forensic Science Society·D Wells
Nov 9, 2002·Journal of Analytical Toxicology·Adam NegruszPhilip G Janicak
May 14, 2003·Forensic Science International : Synergy·Giampietro FrisonSanto Davide Ferrara
Aug 9, 2005·Journal of Clinical Forensic Medicine·I HindmarchS Salamone

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Citations

May 23, 2006·Analytical and Bioanalytical Chemistry·Mitsuhiro Wada, Kenichiro Nakashima
Jan 6, 2006·The New England Journal of Medicine·Georges MionYves Diraison
Sep 2, 2006·Chemical & Pharmaceutical Bulletin·Frédérique KlupschMichel Lhermitte
Dec 4, 2004·Clinical Chemistry and Laboratory Medicine : CCLM·Marion VillainPascal Kintz
Feb 7, 2012·Bioanalysis·Milena Araújo Tonon, Pierina Sueli Bonato
Jul 10, 2010·Toxicology Mechanisms and Methods·R J Dinis-OliveiraT Magalhães
Mar 6, 2009·Forensic Science International : Synergy·Riccardo RossiNadia Fucci
Jan 5, 2008·Mayo Clinic Proceedings·Karen E MoellerJulie C Kissack
May 8, 2007·Emergency Medicine Clinics of North America·Laura K Bechtel, Christopher P Holstege
Jan 9, 2007·Forensic Science International : Synergy·Pascal KintzVincent Cirimele
Sep 22, 2006·Rapid Communications in Mass Spectrometry : RCM·Jin Young KimJeong-Han Kim
Aug 21, 2012·Journal of Forensic Sciences·Cristiana GambelungheRiccardo Rossi
Sep 6, 2005·Forensic Science International : Synergy·P KintzG Pépin
Mar 15, 2005·Journal of Clinical Forensic Medicine·Pascal KintzBertrand Ludes
Sep 29, 2004·Forensic Science International : Synergy·Pascal KintzBertrand Ludes
Jul 4, 2006·Forensic Science International : Synergy·Frank Musshoff, Burkhard Madea
Apr 21, 2006·Clinica Chimica Acta; International Journal of Clinical Chemistry·Fritz Pragst, Marie A Balikova
Apr 25, 2016·Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences·Beril AnilanmertMünevver Açikkol
Jul 29, 2016·Therapeutic Drug Monitoring·Cristiana GambelungheRiccardo Rossi
Dec 29, 2012·Trauma, Violence & Abuse·Ricardo Jorge Dinis-Oliveira, Teresa Magalhães
Jun 17, 2006·Therapeutic Drug Monitoring·Pascal KintzVincent Cirimele
Mar 28, 2008·Therapeutic Drug Monitoring·Pascal KintzVincent Cirimele
Mar 28, 2008·Therapeutic Drug Monitoring·Marc A LeBeau
Mar 4, 2005·The Journal of Pharmacology and Experimental Therapeutics·Karl B ScheidweilerMarilyn A Huestis
Aug 6, 2020·Journal of Analytical Toxicology·Erin C StricklandMark L Miller
Jan 27, 2005·Journal of Mass Spectrometry : JMS
Aug 5, 2006·Thérapie·Pauline Saint-MartinElisabeth Autret-Leca

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