PMID: 15348458Sep 7, 2004Paper

Testing the cytotoxicity of metal alloys used as magnetic prosthetic devices

Journal of Materials Science. Materials in Medicine
M HoppTh Groth

Abstract

Technical magnetic materials are increasingly used for the development of magnetic retained dental prosthetic and orofacial epithetic devices. Since most of the magnets based on rare earth metals, such as samarium-cobalt based alloys have a high tendency for corrosion they were first coated by tin and then encapsulated by titanium. However, the high mechanical load particularly on dental devices may cause a rupture of the titanium capsule and the alloys contact directly biological fluids. Hence, it is important to know the cytotoxicity of these magnets to assess their potential effects on the surrounding tissue. In this study, the cytotoxicity of neodymium-iron-boron and samarium-cobalt (plain, tin and titanium coated) magnets was tested. First, magnets were incubated up to 7 days in culture medium to prepare extracts for cytotoxicity measurements. Changes in the surface morphology due to corrosion were visualized by scanning electron microscopy and analysis of the elemental composition. 3T3 mouse fibroblasts were cultured in the presence of extracts and their viability measured by neutral red and metabolic assays. To learn more about a possible toxic activity of the main components of magnets, salt solutions of different conce...Continue Reading

Citations

Jul 2, 2009·Journal of Biomedical Materials Research. Part a·Gautom Kumar DasTimothy Thatt Yang Tan
Feb 22, 2013·Journal of Clinical Periodontology·Shin Hye ChungYoung-Seok Park
Feb 13, 2009·Journal of Prosthodontics : Official Journal of the American College of Prosthodontists·Arne F BoecklerJuergen M Setz
Aug 28, 2019·Science Robotics·Yoonho KimXuanhe Zhao
Jun 18, 2021·Scientific Reports·Carlos RumboJuan Antonio Tamayo-Ramos

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