Testosterone concentrations and oligomenorrhea in women with acne

International Journal of Dermatology
S HasinskiJ L Miller

Abstract

Androgen excess is frequently associated with oligomenorrhea as well as acne. Oligomenorrhea in hirsute women has been demonstrated to be associated with higher active testosterone levels than found in eumenorrheic hirsute women. This study was designed to evaluate whether similar findings are present in women with acne. Forty-four consecutive women with acne were evaluated by measuring their levels of total testosterone, biologically active testosterone, and free testosterone. The women with oligomenorrhea and acne had significantly higher levels of biologically active testosterone than those with eumenorrhea and acne. This implies that biological active testosterone should be measured in oligomenorrheic women with acne and, if elevated, consideration should be given to antiandrogen therapy. Data were collected from 44 consecutive Caucasian women aged 14 to 38 years. The patients were separated into two groups based on menstrual history. Group 1 had regular menses, and group 2 had oligomenorrhea, defined as menstrual intervals of greater than 36 days. All patients had blood samples drawn on their initial office visit, regardless of the phase of the menstrual cycle, and the levels of total testosterone (TT), biologically active...Continue Reading

Citations

Aug 22, 2000·The British Journal of Dermatology·D CibulaJ Zivny
Jun 19, 2012·Journal of the European Academy of Dermatology and Venereology : JEADV·E TrakakisD Kassanos
Jan 13, 2001·Dermatologic Clinics·J C Shaw
Jun 6, 2009·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·Sudhindra Mohan Bhattacharya
Mar 12, 2019·BioMed Research International·Yu-Yang WangXiao-Hong Li

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