Tests of autonomic dysfunction in patients with multiple sclerosis

Acta Neurologica Scandinavica
V E DroryA D Kroczyn

Abstract

Autonomic dysfunction is frequent in patients with multiple sclerosis (MS). The sympathetic skin response (SSR) and the R-R interval variation (RRIV) are simple electrophysiologic tests for the assessment of central and peripheral autonomic disturbances. Both tests were performed in 60 patients with clinically definite MS and 30 controls. The SSR was recorded simultaneously from both upper and both lower limbs. In all volunteers normal responses were recorded from the four limbs, but 39 patients (65%) showed abnormal responses in at least one limb. The reduction in amplitude of the response was correlated with patients' EDSS. In individual limbs, the SSR amplitude correlated with weakness, spasticity and cerebellar dysfunction, but was not sufficiently related to the deep sensory loss. The RRIV was abnormal in 48 MS patients (80%), as compared to the controls, but showed no significant relationship either to the EDSS or to the SSR. The sensitivity of SSR and RRIV is high and compatible with that of visual and somatosensory evoked potentials.

References

Aug 1, 1991·Journal of the Neurological Sciences·J R AnemaC H Polman
Jan 1, 1972·Brain : a Journal of Neurology·N E Cartlidge
Feb 1, 1968·Journal of Neurology, Neurosurgery, and Psychiatry·M J NoronhaH Aziz
May 1, 1984·Journal of Neurology, Neurosurgery, and Psychiatry·B T ShahaniJ Cohen
Sep 1, 1984·Journal of Neurology, Neurosurgery, and Psychiatry·M P SenaratneT Kappagoda
Mar 1, 1983·Annals of Neurology·C M PoserW W Tourtellotte
Nov 1, 1982·Archives of Neurology·S HaldemanB Johnson
Jan 1, 1981·International Rehabilitation Medicine·P O Lundberg
Feb 1, 1995·Muscle & Nerve·B Elie, J P Louboutin
Aug 1, 1993·Journal of the Neurological Sciences·J A GutrechtB E Denny
Sep 1, 1993·Neurology·V E Drory, A D Korczyn
May 15, 1965·British Medical Journal·H MILLERW K YEATES

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Citations

Jun 1, 1997·Acta Neurologica Scandinavica·J ZiaberJ H Goch
Apr 20, 2002·American Journal of Physical Medicine & Rehabilitation·Tsui Fen YangTerry B J Kuo
Jul 18, 2002·Multiple Sclerosis : Clinical and Laboratory Research·R EggT Berger
Feb 13, 2001·Cephalalgia : an International Journal of Headache·M De Marinis
Nov 3, 2006·Clinical Autonomic Research : Official Journal of the Clinical Autonomic Research Society·Elisabeth ChroniVassiliki Sirrou
Mar 22, 2008·Acta Neurologica Scandinavica·A SaariV V Myllylä
Jul 7, 2007·Multiple Sclerosis : Clinical and Laboratory Research·Yaprak SeçilCumhur Ertekin
Oct 26, 2005·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·A A ArgyriouE Chroni
Feb 7, 1998·American Journal of Physical Medicine & Rehabilitation·T F YangT J Liu
Jul 27, 2006·Acta Neurologica Scandinavica·Ferit AkgülFatih Yalçin
May 2, 2008·Clinical Autonomic Research : Official Journal of the Clinical Autonomic Research Society·Ahmet YildizAbdullah Arslan
Feb 16, 2006·Journal of Neurology·Carl-Albrecht Haensch, Johannes Jörg
Oct 1, 2017·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Nicolò MargaritellaLuigi Pugnetti
Dec 5, 2000·Movement Disorders : Official Journal of the Movement Disorder Society·M De MarinisN Accornero

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