PMID: 7015184Mar 10, 1981Paper

Tetanus toxin: a marker of amphibian neuronal differentiation in vitro

Neuroscience Letters
T Vulliamy, E A Messenger

Abstract

Tetanus toxin may be used to specifically mark neurones in cultures of mammalian and chick nervous tissue. We have prepared cultures of neural ectoderm and underlying mesoderm from late neurula Xenopus laevis embryos, and shown that in this Amphibian species, neurones are labelled by tetanus toxin. Aggregate cultures of ectoderm and mesoderm from late blastula embryos were than examined to determine whether tetanus toxin might be used to mark neuronal precursor cells. Our observations suggest that this is not possible; neurones are seen to have acquired tetanus toxin receptors only after they have become morphologically differentiated.

References

Dec 1, 1977·British Journal of Pharmacology·E A Messenger, A E Warner
Nov 1, 1978·Cell·M C RaffA Hornby-Smith
Jun 9, 1978·Brain Research·R MirskyD Bray
Jan 1, 1979·Annual Review of Neuroscience·N C Spitzer
May 1, 1976·Proceedings of the National Academy of Sciences of the United States of America·N C Spitzer, J E Lamborghini
Sep 24, 1975·Naunyn-Schmiedeberg's Archives of Pharmacology·W DimpfelE Habermann
Mar 1, 1980·Neuroscience Letters·P G Kennedy, R P Lisak

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Citations

Sep 23, 1982·Brain Research·R BealeN N Osborne
Jun 1, 1985·The Journal of Applied Bacteriology·S N Bowring, J G Morris

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