Tetracaine (ametop) compared to placebo for reducing pain associated with intramuscular injection of palivizumab (synagis)

Journal of Pediatric Nursing
Brandi D NewbyCheryl I Soukoroff

Abstract

Infants receive many painful immunizations before they are 2 years old. The purpose of this study was to evaluate if topical tetracaine reduces the pain of intramuscular palivizumab compared to placebo. There were two study injections, one with tetracaine and one with placebo. Pain was scored by their parents and a pediatric nurse. Topical tetracaine was not associated with a significant reduction in pain score, although it did lead to faster recovery times. Additional pain-reduction strategies are required.

References

Mar 10, 1998·Archives of Pediatrics & Adolescent Medicine·S J WeismanN L Schechter
Feb 15, 2001·Archives of Pediatrics & Adolescent Medicine·K J Anand, UNKNOWN International Evidence-Based Group for Neonatal Pain
Nov 13, 2001·The Pediatric Infectious Disease Journal·A S MeyerhoffR J Jacobs
Aug 9, 2003·Advances in Neonatal Care : Official Journal of the National Association of Neonatal Nurses·Mae M ColemanChristine Smith
May 22, 2008·Journal of Pediatric Nursing·Colleen M LaceyMegan V Thygeson

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Citations

Jan 8, 2011·Value in Health : the Journal of the International Society for Pharmacoeconomics and Outcomes Research·Leonard KrilovParthiv J Mahadevia
Apr 5, 2017·Current Opinion in Supportive and Palliative Care·Fiona MoultrieCaroline Hartley
Jan 15, 2016·Applied Clinical Informatics·L H UtidjianR W Grundmeier

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