PMID: 5909587Mar 25, 1966

Tetraethylammonium and tetrodotoxin: effects on cochlear potentials

Science
Y KatsukiJ Kanzaki

Abstract

Tetraethylammonium chloride, which is believed to decrease potassium conductance, and tetrodotoxin, which apparently decreases sodium conductance in nerve fibers, were introduced iontophoretically into the organ of Corti or the scala media of guinea pig cochlea. The former depressed the direct-current endocochlear potential and also the alternating-current cochlear microphonics (the receptor potential of the ear), but tetrodotoxin was ineffective except on the nerve impulses.

Citations

May 1, 1977·The Laryngoscope·R ThalmannS Paloheimo
Dec 1, 1983·Hearing Research·M S KaplanT F Weiss
Aug 15, 1990·Hearing Research·P Weisleder, E W Rubel
Aug 1, 1995·Hearing Research·M G van EmstG F Smoorenburg
Dec 24, 2005·ORL; Journal for Oto-rhino-laryngology and Its Related Specialties·Hirotaka HaraHiroshi Yamashita

Related Concepts

Cochlear Structure
Cavia porcellus
Nerve Conduction Function
Tetramon
Tetrodotoxin
Toxin

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