PMID: 6018645Mar 10, 1967Paper

Tetraethylammonium ions: effect of presynaptic injection on synaptic transmission

Science
K KusanoR Werman

Abstract

Tetraethylammonium ions were injected into the presynaptic axon of the squid giant synapse. Injection of these ions caused prolongation of the action potential with decreased out ward current. The prolonged spike was associated with increased release and prolonged activity of the transmitter substance. Although the amplitude of the postsynaptic potential increased with presynaptic depolarization, strong depolarization blocked transmitter re lease. In the injected presynaptic axon, transmitter release was blocked by 10(-6) gram of tetrodotoxin per milliliter. Transmitter release appears to be under control of presynaptic potential levels.

References

Sep 4, 1965·Nature·P J Garrahan, I M Glynn
May 1, 1966·The Journal of Physiology·R Miledi, C R Slater
Sep 1, 1966·The American Journal of Physiology·I TasakiA Watanabe
Mar 20, 1957·The Journal of General Physiology·T H BULLOCK, S HAGIWARA
Jul 20, 1957·The Journal of General Physiology·I TASAKI, A S HAGIWAR
Apr 1, 1958·The American Journal of Physiology·K KOKETSU
Aug 29, 1958·The Journal of Physiology·S HAGIWARA, I TASAKI
Jul 1, 1962·The Journal of General Physiology·A TAKEUCHI, N TAKEUCHI
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Jul 1, 1948·Journal of Neurophysiology·T H BULLOCK
Dec 10, 1966·Nature·B Katz, R Miledi

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Citations

Aug 15, 1968·Experientia·H L Atwood
Jan 1, 1976·Progress in Neurobiology·H L Atwood
Apr 15, 1977·Experientia·K G Morgan, S H Bryant
Aug 24, 1989·Nature·A N SpencerT A Basarsky
Jan 1, 1970·Journal of Neurobiology·K Kusano

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