Tetralogy of Fallot with major aortopulmonary collaterals: early total repair

Pediatric Cardiology
D B McElhinneyF L Hanley

Abstract

Tetralogy of Fallot with pulmonary atresia and major aortopulmonary collaterals is a complex lesion distinguished by marked heterogeneity of pulmonary blood supply. Over the past two decades, investigators have developed various approaches to the management of this anomaly generally based on the concept of staged unifocalization of pulmonary blood supply. Although such approaches may represent an improvement on the natural history of this lesion, they remain inadequate for a substantial portion of patients born with tetralogy of Fallot and major aortopulmonary collaterals. Since 1992, our approach has been to perform one-stage complete unifocalization through a midline approach in all but a few extremely complicated patients. We aim to repair these patients early in infancy, with an emphasis on native tissue-tissue reconstruction, in order to optimize prospects for survival with a good functional outcome in as many patients as possible. In this review, we present our philosophy and our experience with unifocalization and repair in 72 patients.

Citations

Jan 17, 2002·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Mark VranicarPhillip Moore
Mar 24, 2006·Pediatric Radiology·Gerald F GreilLudger Sieverding
Sep 23, 2003·The Journal of Thoracic and Cardiovascular Surgery·Elisabeth I van DongenDesmond Bohn
Mar 25, 2004·AJR. American Journal of Roentgenology·Kevin J RocheNancy B Genieser
Jun 25, 2010·Journal of Cardiothoracic and Vascular Anesthesia·Madan Mohan MaddaliBoris Dimitrov Dimitrov
Nov 3, 2009·Journal of Veterinary Cardiology : the Official Journal of the European Society of Veterinary Cardiology·Yoko FujiiYoshito Wakao
Nov 5, 1999·Radiologic Clinics of North America·J L Strife, R W Sze
Mar 11, 2010·Journal of Thoracic Imaging·Robyn D GartnerLinda B Haramati
May 27, 2020·Seminars in Cardiothoracic and Vascular Anesthesia·Madhusudan GanigaraSathish M Chikkabyrappa
Apr 25, 2019·The International Journal of Cardiovascular Imaging·Evan J ZuckerFrandics P Chan
Jan 8, 2021·World Journal for Pediatric & Congenital Heart Surgery·Ariana GoodmanDoff B McElhinney

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.