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Tetramethoxydibenzoquinolizinium salts. Preparation and antileukemic activity of some positional and structural isomers of coralyne

Journal of Medicinal Chemistry

Jul 1, 1976

R K Zee-Cheng, C C Cheng

PMID: 940108

Abstract

Some positional and structural isomers of coralyne were prepared and evaluated in the P388 lymphocytic leukemia system for their inhibitory activity. The levels of antileukemic activity of coralyne, neocoralyne, isocoralyne, and stracoralyne were comparable, thus implying that two sets ...read more

Mentioned in this Paper

Antineoplastic Agents
Coralyne
Structure-Activity Relationship
Leukemia, Experimental
Isoquinolines
Chromosome Condensation
Isomerism
Pharmacophore
Quaternary Ammonium Compounds
Salts
Paper Details
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Tetramethoxydibenzoquinolizinium salts. Preparation and antileukemic activity of some positional and structural isomers of coralyne

Journal of Medicinal Chemistry

Jul 1, 1976

R K Zee-Cheng, C C Cheng

PMID: 940108

DOI:

Abstract

Some positional and structural isomers of coralyne were prepared and evaluated in the P388 lymphocytic leukemia system for their inhibitory activity. The levels of antileukemic activity of coralyne, neocoralyne, isocoralyne, and stracoralyne were comparable, thus implying that two sets ...read more

Mentioned in this Paper

Antineoplastic Agents
Coralyne
Structure-Activity Relationship
Leukemia, Experimental
Isoquinolines
Chromosome Condensation
Isomerism
Pharmacophore
Quaternary Ammonium Compounds
Salts

Similar Papers Found In These Feeds

Lymphoid Neoplasms

Lymphoid neoplasms are derived from cells that frequently have features that recapitulate stages of normal b-, t-, and nk-cell differentiation and function. Lymphoid neoplasms include the following morphologic types: follicular center cell, lymphoblast (lymphocytic), immunoblast, plasma cell, and large granular lymphocyte (lgl). Here is the latest research on lymphoid neoplasms.

Related Papers

Journal of Medicinal Chemistry

Experimental antileukemic agents. Coralyne, analogs, and related compounds

Journal of Medicinal ChemistryMarch 1, 1974
K Y Zee-ChengC C Cheng
Journal of Medicinal Chemistry

Coralyne. Intercalation with DNA as a possible mechanism of antileukemic action

Journal of Medicinal ChemistryOctober 1, 1976
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Paper Details
References
  • References
  • Citations10
  • finger pointing at paper

    References currently unavailable

    We're still populating references for this paper, please check back later.
  • References
  • Citations10
1
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