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TFAP4-uORF coding 66aa inhibits the malignant behavior of glioma cells via suppressing TFAP4/LINC00520/miR-520f-3p feedback loop

Cancer Science

Jan 17, 2020

Yipeng WangYunhui Liu

Abstract

Upstream open reading frame (uORF) is a translational initiation element located in the 5' untranslated region (5'UTR) of eukaryotic mRNAs. Studies have found that uORFs play an important regulatory role in many diseases. Based on the TCGA database, the results of our experiments and pr...read more

Mentioned in this Paper

MicroRNAs
Translation Initiation
Binding (Molecular Function)
Down-Regulation
3' Untranslated Regions
Cell Invasion
Gene Knockdown Techniques
Dalfampridine
Promoter Regions, Genetic
Migration, Cell
Paper Details
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TFAP4-uORF coding 66aa inhibits the malignant behavior of glioma cells via suppressing TFAP4/LINC00520/miR-520f-3p feedback loop

Cancer Science

Jan 17, 2020

Yipeng WangYunhui Liu

PMID: 31943575

DOI: 10.1111/cas.14308

Abstract

Upstream open reading frame (uORF) is a translational initiation element located in the 5' untranslated region (5'UTR) of eukaryotic mRNAs. Studies have found that uORFs play an important regulatory role in many diseases. Based on the TCGA database, the results of our experiments and pr...read more

Mentioned in this Paper

MicroRNAs
Translation Initiation
Binding (Molecular Function)
Down-Regulation
3' Untranslated Regions
Cell Invasion
Gene Knockdown Techniques
Dalfampridine
Promoter Regions, Genetic
Migration, Cell

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Cell Migration

Cell migration is involved in a variety of physiological and pathological processes such as embryonic development, cancer metastasis, blood vessel formation and remoulding, tissue regeneration, immune surveillance and inflammation. Here is the latest research.

MicroRNAs & Open Reading Frames

MicroRNAs are small non-coding RNAs that modulate gene expression at post-transcriptional level, playing a crucial role in cell differentiation and development. Discover the latest research on MicroRNAs & how they target Open Reading Frames.

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DGCR8/ZFAT-AS1 Promotes CDX2 Transcription in a PRC2 Complex-Dependent Manner to Facilitate the Malignant Biological Behavior of Glioma Cells

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Paper Details
References
  • References44
  • Citations
12345
  • References44
  • Citations
  • quote and clock

    No citations available

    This paper may not have been cited yet.
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