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TGF-β Signaling in Cellular Senescence and Aging-Related Pathology

International Journal of Molecular Sciences

Oct 10, 2019

Kana Tominaga, Hiroshi I Suzuki

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Abstract

Aging is broadly defined as the functional decline that occurs in all body systems. The accumulation of senescent cells is considered a hallmark of aging and thought to contribute to the aging pathologies. Transforming growth factor-β (TGF-β) is a pleiotropic cytokine that regulates a m...read more

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Aging
Alzheimer's Disease
Cell Aging
Embryonic Development
Fibrosis
Inflammation
Ligands
Muscular Atrophy
Obesity
Natural Regeneration
1
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TGF-β Signaling in Cellular Senescence and Aging-Related Pathology

International Journal of Molecular Sciences

Oct 10, 2019

Kana Tominaga, Hiroshi I Suzuki

PMID: 31658594

DOI: 10.3390/ijms20205002

Abstract

Aging is broadly defined as the functional decline that occurs in all body systems. The accumulation of senescent cells is considered a hallmark of aging and thought to contribute to the aging pathologies. Transforming growth factor-β (TGF-β) is a pleiotropic cytokine that regulates a m...read more

Mentioned in this Paper

Aging
Alzheimer's Disease
Cell Aging
Embryonic Development
Fibrosis
1

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