PMID: 819108Jun 25, 1976Paper

Thalamic projections of the dorsomedial prefrontal cortex in the rhesus monkey (Macaca mulatta)

Brain Research
D Tanaka

Abstract

Cortical aspirations were made of the dorsomedial prefrontal sector in the rhesus monkey and the resultant anterograde and retrograde degeneration plotted. Retrograde changes were mapped using both cresyl violet and modified Fink-Heimer techniques. Following large dorsomedial lesions, small numbers of degenerating fibers were traced through the medial part of the magnocellular ventral anterior nucleus (VAmc) and the ventral part of the internal medullary lamina surrounding the anterior nuclei. Degenerating fibers were also traced medially through the inferior thalamic peduncle and rostrodorsally through the basal thalamic region into the mediodorsal nucleus. All pathways converged on areas in the dorsal part of the parvocellular mediodorsal nucleus (MDpc) containing fine-grain dust and argyrophilic neurons, reactions usually associated with retrograde degenerative changes. Sparse fiber degeneration was also noted in the ventral part of the magnocellular mediodorsal nucleus (MDmc). After a longer survival period, slight to moderate cell loss and gliosis were seen in MDpc along with an increase in the number of degenerating fibers passing through the medial part of VAmc. Rostral dorsomedial lesions resulted in small numbers of de...Continue Reading

References

Jul 1, 1974·Experimental Neurology·H Lin, W R Ingram
Jan 1, 1972·Brain, Behavior and Evolution·C M Leonard
Mar 1, 1970·Journal of Comparative and Physiological Psychology·J S Stamm
Jun 1, 1953·The Journal of Comparative Neurology·K H PRIBRAMJ SEMMES
Mar 1, 1954·Stain Technology·M H ALBRECHT
Oct 1, 1963·The Journal of Comparative Neurology·G SCOLLO-LAVIZZARI, K Akert
Dec 1, 1964·The Journal of Comparative Neurology·J L DEVITO, O A SMITH
Aug 1, 1950·Journal of Neurology, Neurosurgery, and Psychiatry·P GLEESH CAIRNS

Citations

Oct 16, 2012·Neuropsychology Review·Carly S MolloyPeter J Anderson
Jan 1, 1986·Progress in Neurobiology·S F Takagi
Sep 1, 1986·Brain Research Bulletin·A J McDonald, J L Culberson
Jan 1, 2011·Brain Connectivity·Kyle TaljanKen Sakaie
Feb 11, 1998·Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society·N MikuniH Shibasaki
Aug 10, 2005·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·T E J Behrens, H Johansen-Berg
Dec 31, 2005·Journal of Neurosurgery·E L SilleryH Johansen-Berg
Apr 11, 2012·Human Brain Mapping·Hendrick StrumpfJens-Max Hopf
Sep 11, 2012·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·Gareth BallSerena J Counsell
Nov 11, 2014·NeuroImage. Clinical·Megan L McGillThomas Thesen
Oct 16, 2016·Human Brain Mapping·Samantha I CunninghamNora D Volkow
Oct 31, 2003·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·T E J BehrensS M Smith
May 13, 2017·Brain Connectivity·Vitalie ChiosaSergiu Groppa
Dec 8, 2006·Journal of Magnetic Resonance Imaging : JMRI·Mojtaba ZareiP M Matthews
Jun 8, 1988·The Journal of Comparative Neurology·S Y Musil, C R Olson
Mar 15, 1979·The Journal of Comparative Neurology·J A Weisberg, A Rustioni
May 11, 2018·Molecular Psychiatry·Euripedes C MiguelSameer A Sheth
Jan 1, 1985·Annals of the New York Academy of Sciences·G W Van Hoesen
Jun 1, 2018·Cerebral Cortex·Nicola Palomero-GallagherKarl Zilles

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Hereditary Sensory Autonomic Neuropathy

Hereditary Sensory Autonomic Neuropathies are a group of inherited neurodegenerative disorders characterized clinically by loss of sensation and autonomic dysfunction. Here is the latest research on these neuropathies.

Spatio-Temporal Regulation of DNA Repair

DNA repair is a complex process regulated by several different classes of enzymes, including ligases, endonucleases, and polymerases. This feed focuses on the spatial and temporal regulation that accompanies DNA damage signaling and repair enzymes and processes.

Glut1 Deficiency

Glut1 deficiency, an autosomal dominant, genetic metabolic disorder associated with a deficiency of GLUT1, the protein that transports glucose across the blood brain barrier, is characterized by mental and motor developmental delays and infantile seizures. Follow the latest research on Glut1 deficiency with this feed.

Separation Anxiety

Separation anxiety is a type of anxiety disorder that involves excessive distress and anxiety with separation. This may include separation from places or people to which they have a strong emotional connection with. It often affects children more than adults. Here is the latest research on separation anxiety.

KIF1A Associated Neurological Disorder

KIF1A associated neurological disorder (KAND) is a rare neurodegenerative condition caused by mutations in the KIF1A gene. KAND may present with a wide range and severity of symptoms including stiff or weak leg muscles, low muscle tone, a lack of muscle coordination and balance, and intellectual disability. Find the latest research on KAND here.

Regulation of Vocal-Motor Plasticity

Dopaminergic projections to the basal ganglia and nucleus accumbens shape the learning and plasticity of motivated behaviors across species including the regulation of vocal-motor plasticity and performance in songbirds. Discover the latest research on the regulation of vocal-motor plasticity here.