Thalamocortical synapses involving identified neurons in mouse primary somatosensory cortex: a terminal degeneration and golgi/EM study

The Journal of Comparative Neurology
S M Hersch, E L White

Abstract

Synapses involving thalamocortical afferents and hitherto unexamined neuron types of the posteromedial barrel subfield (PMBSF) of the mouse have been identified using a combined degeneration and Golgi/EM technique (Peters et al., '77). Degeneration of thalamocortical axon terminals was produced with electrolytic lesions of the nucleus ventralis posterior, pars lateralis thalami, and the nucleus posterior thalami. Four days after receiving lesions, the animals were perfused, and blocks of cortex containing the PMBSF were processed by the Golgi method. The blocks were tissue-chopped at 125 microns and examined with the light microscope. Sections containing neurons of interest were gold-toned and deimpregnated in preparation for electron microscopy (Fairén et al., '77). Portions of selected neurons contained in layers III-IV were serially thin-sectioned and examined with an electron microscope to determine if they were involved in synapses with degenerating thalamocortical axon terminals. Results showed thalamocortical synapses on the apical dendrites of five different sized pyramidal cells whose somata occurred in layers V and VI, and on dendrites of on spiny bitufted neuron and one non-spiny multipolar neuron with somata in laye...Continue Reading

References

Sep 15, 1977·The Journal of Comparative Neurology·S P Wise, E G Jones
Jan 29, 1970·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·E G Jones, T P Powell
Feb 15, 1973·The Journal of Comparative Neurology·J S Lund
Mar 11, 1969·Proceedings of the Royal Society of London. Series B, Containing Papers of a Biological Character·E G Jones, T P Powell
Oct 12, 1971·Proceedings of the Royal Society of London. Series B, Containing Papers of a Biological Character·L J Garey
Jan 1, 1968·Experimental Brain Research·F Valverde
Nov 1, 1967·Experimental Neurology·A Globus, A B Scheibel

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Citations

Apr 1, 1983·Journal of Neurocytology·S H Hendry, E G Jones
Oct 1, 1992·Progress in Neurobiology·M Kossut
Feb 3, 2007·Brain Research Reviews·Alan Peters
Jan 1, 1989·Acta Neurologica Scandinavica. Supplementum·J Carlsen
Nov 1, 1984·The Journal of Comparative Neurology·E L WhiteS M Hersch
Mar 1, 1994·The Journal of Comparative Neurology·J C AndersonJ C Nelson
Mar 1, 1981·The Journal of Comparative Neurology·R M Harris, T A Woolsey
May 1, 1981·The Journal of Comparative Neurology·E L White, S M Hersch
Aug 1, 1987·The Journal of Comparative Neurology·A Keller, E L White

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