Thalassemias in South Asia: clinical lessons learnt from Bangladesh

Orphanet Journal of Rare Diseases
Mohammad Sorowar HossainManzur Morshed

Abstract

Thalassemias are emerging as a global public health concern. Due to remarkable success in the reduction of childhood mortality by controlling infectious diseases in developing countries, thalassemias are likely to be a major public health concern in the coming decades in South Asia. Despite the fact that Bangladesh lies in the world's thalassemia belt, the information on different aspects (epidemiology, clinical course, mortality, complications and treatment outcomes) of thalassemias is lacking. In this comprehensive review, the aim is to to depict the epidemiological aspects of thalassemias, mutation profile and current treatment and management practices in the country by sharing the experience of dealing with 1178 cases over 2009-2014 time periods in a specialized thalassemia treatment centre. We have also discussed the preventative strategies of thalassemias from the context of Bangladesh which could be effective for other developing countries.

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Citations

Aug 7, 2019·Annals of the New York Academy of Sciences·Paloma K Barrera-Reyes, M Elizabeth Tejero
Feb 23, 2020·Orphanet Journal of Rare Diseases·Mohammad Sorowar HossainMahbubul H Siddiqee
Mar 28, 2018·Journal of Immigrant and Minority Health·Alexandra JablonkaChristine Happle
Nov 16, 2018·Annals of Laboratory Medicine·Hyun Ji LeeMoon Woo Seong
Apr 20, 2019·BioMed Research International·Achraf LaghmichMohcine Bennani Mechita
Dec 1, 2018·Maternal & Child Nutrition·Rebecca K CampbellKeith P West
Jun 26, 2020·Frontiers in Medicine·Sanjana Fatema Chowdhury, Saeed Anwar
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Apr 23, 2020·Journal of Family Medicine and Primary Care·Babita RaghuwanshiDurgesh Prasad Sahoo
Jul 23, 2020·Journal of Religion and Health·Muhammad Abo Ul Hassan RashidMalik Maliha Manzoor
Oct 29, 2020·Journal of Family Medicine and Primary Care·Nitu NigamMadan Lal Brahma Bhatt
Jan 28, 2021·Dental press journal of orthodontics·Waqar JeelaniMaheen Ahmed
Apr 11, 2021·Orphanet Journal of Rare Diseases·Mohammad Jakir HosenOlivier M Vanakker
Jul 3, 2021·Journal of Basic and Clinical Physiology and Pharmacology·Hasna QatrunnadaSiti Wahyuni
Jul 18, 2021·Orphanet Journal of Rare Diseases·Mohammad Sorowar HossainAbdullah Al Mosabbir
Sep 9, 2021·Public Health in Practice·Mohammad Sorowar HossainAbdullah Al Mosabbir
Sep 27, 2020·Orphanet Journal of Rare Diseases·Mohammad Sorowar HossainMahbubul H Siddiqee
Nov 6, 2021·Molecular Genetics & Genomic Medicine·Shaukat AliMuhammad Adeeb Khan

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