Thalidomide and its analogues as cyclooxygenase inhibitors

Bioorganic & Medicinal Chemistry Letters
Tomomi NoguchiYuichi Hashimoto

Abstract

Thalidomide showed cyclooxygenase (COX)-1/2 inhibitory activity with a potency comparable to that of aspirin. Structural development studies of thalidomide resulted in potent COX-1/2 inhibitors, and COX-1-selective and COX-2-selective inhibitors.

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Citations

Aug 2, 2005·Journal of Computer-aided Molecular Design·Hwangseo Park, Sangyoub Lee
Jun 7, 2005·Bioorganic & Medicinal Chemistry Letters·Tomomi NoguchiYuichi Hashimoto
May 20, 2003·Seminars in Dialysis·Lara B Pupim, T Alp Ikizler
Aug 10, 2002·Journal of Cellular and Molecular Medicine·S KumarS V Rajkumar
Mar 4, 2005·Biological & Pharmaceutical Bulletin·Tomomi NoguchiYuichi Hashimoto
Sep 3, 2003·Chemical & Pharmaceutical Bulletin·Mamiko SuizuYuichi Hashimoto
Apr 2, 2004·Chemical & Pharmaceutical Bulletin·Rumiko ShimazawaYuichi Hashimoto
Jul 2, 2011·Chemical & Pharmaceutical Bulletin·Kazunori MotoshimaKazuyuki Sugita
Jun 2, 2007·World Journal of Urology·Bernard PauleAlexandre de la Taille
Mar 15, 2006·Seminars in Nephrology·Lara B PupimT Alp Ikizler
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Jun 16, 2004·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Shaji KumarS Vincent Rajkumar
Apr 6, 2005·Bioorganic & Medicinal Chemistry·Hiroko SanoHiroyuki Miyachi
Mar 4, 2006·Bioorganic & Medicinal Chemistry Letters·Hiroko SanoHiroyuki Miyachi
Nov 30, 2013·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Samir H Bouayad-Gervais, William D Lubell
Nov 9, 2018·The Journal of Toxicological Sciences·Ana Mara Islas-EspinozaEduardo Ramírez San Juan
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Dec 23, 2020·Journal of Proteome Research·Mostafa JamalanFathollah Gholami-Borujeni
Mar 11, 2011·European Journal of Medicinal Chemistry·Alaa A-M Abdel-AzizYousif A Asiri

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